Browsing by Author Bartolini, Manuela
Showing results 1 to 10 of 10
| Issue Date | Title | Author(s) |
|---|---|---|
| 12-Feb-2014 | 1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: synthesis, pharmacological evaluation and mechanistic studies | Di Pietro, O.; Viayna, Elisabet; Vicente García, Esther; Bartolini, Manuela; Ramón, Rosario; Juárez-Jiménez, Jordi; Clos, Victòria; Pérez Fernández, Belén; Andrisano, Vincenza; Luque Garriga, F. Xavier; Lavilla Grífols, Rodolfo; Muñoz-Torrero López-Ibarra, Diego |
| 2019 | A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors | Pérez Areales, Francisco Javier; Turcu, Andreea L.; Barniol-Xicota, Marta; Pont Masanet, Caterina; Pivetta, Deborah; Espargaró Colomé, Alba; Bartolini, Manuela; De Simone, Angela; Andrisano, Vincenza; Pérez, Belén; Sabaté Lagunas, Raimon; Sureda, Francesc X.; Vázquez Cruz, Santiago; Muñoz-Torrero López-Ibarra, Diego |
| 2022 | Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease | Codony Gisbert, Sandra; Pont Masanet, Caterina; Griñán Ferré, Christian; Di Pede-Mattatelli, Ania; Calvó-Tusell, Carla; Feixas, Ferran; Osuna, Sílvia; Jarné-Ferrer, Júlia; Naldi, Marina; Bartolini, Manuela; Loza, María Isabel; Brea, José; Bartolini; Pérez, Belén; Bartra, Clara; Sanfeliu i Pujol, Coral; Juárez Jiménez, Jordi; Morisseau, Christophe; Hammock, Bruce D.; Pallàs i Llibería, Mercè, 1964-; Vázquez Cruz, Santiago; Muñoz-Torrero López-Ibarra, Diego |
| 2021 | Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice | Viayna, Elisabet; Coquelle, Nicolas; Cieslikiewicz-Bouet, Monika; Cisternas, Pedro; Oliva, Carolina; Sánchez-López, E. (Elena); Ettcheto Arriola, Miren; Bartolini, Manuela; De Simone, Angela; Ricchini, Mattia; Rendina, Marisa; Pons, Mégane; Firuzi, Omidreza; Pérez, Belén; Saso, Luciano; Andrisano, Vincenza; Nachon, Florian; Brazzolotto, Xavier; García, Maria Luisa; Camins Espuny, Antoni; Silman, Israel; Jean, Ludovic; Inestrosa, Nibaldo C.; Colletier, Jacques-Philippe; Renard, Pierre-Yves; Muñoz-Torrero López-Ibarra, Diego |
| 2022 | Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer's Disease | Gandini, Annachiara; Gonçalves, Ana Elisa; Strocchi, Silvia; Albertini, Claudia; Janočková, Jana; Tramarin, Anna; Grifoni, Daniela; Poeta, Eleonora; Soukup, Ondrej; Muñoz-Torrero López-Ibarra, Diego; Monti, Barbara; Sabaté Lagunas, Raimon; Bartolini, Manuela; Legname, Giuseppe; Bolognesi, Maria Laura |
| 28-Oct-2020 | Evaluation of the effects of acetylcholinesterase inhibitors in the zebrafish touch-evoked response: quantitative vs. qualitative assessment | Guzman, Laura; Besa, Gisela; Linares, Daniela; González, Lara; Pont Masanet, Caterina; Bartolini, Manuela; Haigis, Ann-Cathrin; Legradi, Jessica; Muñoz-Torrero López-Ibarra, Diego; Gómez Catalán, Jesús; Barenys Espadaler, Marta |
| 2021 | From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects | Pont Masanet, Caterina; Ginex, Tiziana; Griñán Ferré, Christian; Scheiner, Matthias; Mattellone, Alexia; Martínez, Noemí; Arce, Elsa M.; Soriano-Fernández, Yolanda; Naldi, Marina; De Simone, Angela; Barenys Espadaler, Marta; Gómez Catalán, Jesús; Pérez, Belén; Sabaté Lagunas, Raimon; Andrisano, Vincenza; Loza, María Isabel; Brea, José; Bartolini, Manuela; Bolognesi, Maria Laura; Decker, Michael; Pallàs i Llibería, Mercè, 1964-; Luque Garriga, F. Xavier; Muñoz-Torrero López-Ibarra, Diego |
| 11-Mar-2018 | Increasing polarity in tacrine and huprine derivatives: Potent anticholinesterase agents for the treatment of myasthenia gravis | Galdeano Cantador, Carlos; Coquelle, Nicolas; Cieslikiewicz-Bouet, Monika; Bartolini, Manuela; Pérez, Belén; Clos, Victòria; Silman, Israel; Jean, Ludovic; Colletier, Jacques-Philippe; Renard, Pierre-Yves; Muñoz-Torrero López-Ibarra, Diego |
| 27-Mar-2014 | Synthesis and multi-target biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents | Viayna, Elisabet; Sola, Irene; Bartolini, Manuela; De Simone, Angela; Tapia-Rojas, Cheril; Serrano, Felipe G.; Sabaté Lagunas, Raimon; Juárez-Jiménez, Jordi; Pérez Fernández, Belén; Luque Garriga, F. Xavier; Andrisano, Vincenza; Clos, Victòria; Inestrosa, Nibaldo C.; Muñoz-Torrero López-Ibarra, Diego |
| 14-Aug-2019 | Synthesis, in vitro profiling, and in vivo efficacy studies of a new family of multitarget anti-Alzheimer compounds | Pérez Areales, Francisco Javier; Garrido, María; Aso Pérez, Ester; Bartolini, Manuela; De Simone, Angela; Espargaró Colomé, Alba; Ginex, Tiziana; Sabaté Lagunas, Raimon; Pérez, Belén; Andrisano, Vincenza; Luque Garriga, F. Xavier; Ferrer, Isidro (Ferrer Abizanda); Ciruela Alférez, Francisco; Messeguer i Peypoch, Àngel, 1946-; Muñoz-Torrero López-Ibarra, Diego |