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Title: | Acute renal failure induced by acute interstitial nephritis secondary to cocaine |
Author: | Gelpi, Rosana Taco, Omar Gomà, Montse Torras Ambròs, Joan Poveda, Rafael Álvarez, Teresa Grinyó Boira, Josep M. Fulladosa, Xavier |
Keywords: | Insuficiència renal crònica Insuficiència renal aguda Glomerulonefritis Cocaïna Interaccions dels medicaments Chronic renal failure Acute renal failure Glomerulonefritis Cocaine Drug interactions |
Issue Date: | Feb-2013 |
Publisher: | Elsevier España |
Abstract: | Cocaine has been used by 2.6% of the Spanish population aged between 15 and 64 at some point in their life, making it one of the most consumed illegal drugs after cannabis.1 Cocaine use is associated with multiple complications: neurological, cardiovascular, psychiatric, pulmonary, gastrointestinal and nephrological. Renal complications associated with cocaine use have received little attention, despite the existence of several mechanisms, in addition to secondary high blood pressure, that can cause acute renal failure (ARF) or worsen a pre-existing case of chronic renal failure. Drug-induced acute interstitial nephritis (DIAIN) represents a high percentage of acute renal failure in clinical practice. Some studies indicate that DIAIN is the lesion responsible for renal failure in about 15% of biopsies with ARF. Furthermore, in many cases of DIAIN, no biopsy is performed and diagnosis is based on clinical data and recent administration of a new drug which, as described below, is sometimes not very easy to identify. |
Note: | Document publicat també en castellà |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.3265/Nefrología.pre2013.Feb.11809 |
It is part of: | Nefrología, 2013, vol. 33, num. 4, p. 609-611 |
URI: | http://hdl.handle.net/2445/100000 |
Related resource: | http://dx.doi.org/10.3265/Nefrología.pre2013.Feb.11809 |
ISSN: | 0211-6995 |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
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647510.pdf | 62.67 kB | Adobe PDF | View/Open | |
647510_castellà.pdf | 226.74 kB | Adobe PDF | View/Open |
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