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Title: Acute renal failure induced by acute interstitial nephritis secondary to cocaine
Author: Gelpi, Rosana
Taco, Omar
Gomà, Montse
Torras Ambròs, Joan
Poveda, Rafael
Álvarez, Teresa
Grinyo Boira, Josep M.
Fulladosa, Xavier
Keywords: Insuficiència renal crònica
Insuficiència renal aguda
Interaccions dels medicaments
Chronic renal failure
Acute renal failure
Drug interactions
Issue Date: Feb-2013
Publisher: Elsevier España
Abstract: Cocaine has been used by 2.6% of the Spanish population aged between 15 and 64 at some point in their life, making it one of the most consumed illegal drugs after cannabis.1 Cocaine use is associated with multiple complications: neurological, cardiovascular, psychiatric, pulmonary, gastrointestinal and nephrological. Renal complications associated with cocaine use have received little attention, despite the existence of several mechanisms, in addition to secondary high blood pressure, that can cause acute renal failure (ARF) or worsen a pre-existing case of chronic renal failure. Drug-induced acute interstitial nephritis (DIAIN) represents a high percentage of acute renal failure in clinical practice. Some studies indicate that DIAIN is the lesion responsible for renal failure in about 15% of biopsies with ARF. Furthermore, in many cases of DIAIN, no biopsy is performed and diagnosis is based on clinical data and recent administration of a new drug which, as described below, is sometimes not very easy to identify.
Note: Document publicat també en castellà
Note: Reproducció del document publicat a:ía.pre2013.Feb.11809
It is part of: Nefrología, 2013, vol. 33, num. 4, p. 609-611
Related resource:ía.pre2013.Feb.11809
ISSN: 0211-6995
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Articles publicats en revistes (Ciències Clíniques)

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