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http://hdl.handle.net/2445/101573
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DC Field | Value | Language |
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dc.contributor.author | Annamalay, Alicia A. | - |
dc.contributor.author | Lanaspa, Miguel | - |
dc.contributor.author | Khoo, Siew-Kim | - |
dc.contributor.author | Madrid, Lola | - |
dc.contributor.author | Acácio, Sozinho | - |
dc.contributor.author | Zhang, Guicheng | - |
dc.contributor.author | Laing, Ingrid | - |
dc.contributor.author | Gern, James | - |
dc.contributor.author | Goldblatt, Jack | - |
dc.contributor.author | Bizzintino, Joelene | - |
dc.contributor.author | Lehmann, Deborah | - |
dc.contributor.author | Le Souef, Peter N. | - |
dc.contributor.author | Bassat Orellana, Quique | - |
dc.date.accessioned | 2016-09-06T07:06:44Z | - |
dc.date.available | 2017-07-26T22:01:32Z | - |
dc.date.issued | 2016-07-26 | - |
dc.identifier.issn | 1360-2276 | - |
dc.identifier.uri | http://hdl.handle.net/2445/101573 | - |
dc.description.abstract | OBJECTIVES: To describe the prevalence of human rhinovirus (RV) species in children hospitalized with pneumonia in Manhica, Mozambique; and the associations between RV species and demographic, clinical, and laboratory features. METHODS: Nasopharyngeal aspirates were collected from children 0-10 years of age (n=277) presenting to Manhica District Hospital with clinical pneumonia. Blood samples were collected for HIV and malaria testing, blood culture and full blood counts, and a chest X-ray was performed. A panel of common respiratory viruses was investigated using two independent multiplex RT-PCR assays with primers specific for each virus and viral type. RV species and genotypes were identified by semi-nested PCR assays, sequencing and phylogenetic tree analyses. RESULTS: At least one respiratory virus was identified in 206 (74.4%) children hospitalized with clinical pneumonia. RV was the most common virus identified in both HIV-infected (17/38, 44.7%) and HIV-uninfected (74/237, 31.2%; p=0.100) children. RV-A was the most common RV species identified (47/275, 17.0%), followed by RV-C (35/275, 12.6%) and RV-B (8/275, 2.9%). Clinical presentation of the different RV species was similar and overlapping, with no particular species being associated with specific clinical features. CONCLUSIONS: RV-A and RV-C were the most common respiratory viruses identified in children hospitalised with clinical pneumonia in Manhica. Clinical presentation of RV-A and RV-C was similar and overlapping. This article is protected by copyright. All rights reserved. | - |
dc.format.extent | 21 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | John Wiley & Sons | - |
dc.relation.isformatof | Versió postprint del document publicat a: http://dx.doi.org/10.1111/tmi.12743 | - |
dc.relation.ispartof | Tropical Medicine & International Health, 2016 | - |
dc.relation.uri | http://dx.doi.org/10.1111/tmi.12743 | - |
dc.rights | (c) John Wiley & Sons, 2016 | - |
dc.source | Articles publicats en revistes (ISGlobal) | - |
dc.subject.classification | Pneumònia | - |
dc.subject.classification | Infants | - |
dc.subject.classification | Moçambic | - |
dc.subject.other | Pneumonia | - |
dc.subject.other | Children | - |
dc.subject.other | Mozambique | - |
dc.title | Rhinovirus Species and Clinical Features in Children Hospitalized with Pneumonia from Mozambique | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.date.updated | 2016-08-03T18:00:44Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 27353724 | - |
Appears in Collections: | Articles publicats en revistes (ISGlobal) |
Files in This Item:
File | Description | Size | Format | |
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annamalay2016_2169.pdf | 270.97 kB | Adobe PDF | View/Open |
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