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Title: Cafeteria diet induce changes in blood flow that are more related with heat dissipation than energy accretion
Author: Sabater, David
Agnelli, Silvia
Arriarán, Sofía
Romero, María del Mar
Fernández López, José Antonio
Alemany, Marià, 1946-
Remesar Betlloch, Xavier
Keywords: Circulació sanguínia
Rates (Animals de laboratori)
Lípids en la nutrició
Circulation of the blood
Rats as laboratory animals
Lipids in human nutrition
Issue Date: 3-Aug-2016
Publisher: PeerJ
Abstract: Background. A ``cafeteria'' diet is a self-selected high-fat diet, providing an excess of energy, which can induce obesity. Excess of lipids in the diet hampers glucose utilization eliciting insulin resistance, which, further limits amino acid oxidation for energy. Methods. Male Wistar rats were exposed for a month to ``cafeteria'' diet. Rats were cannulated and fluorescent microspheres were used to determine blood flow. Results. Exposure to the cafeteria diet did not change cardiac output, but there was a marked shift in organ irrigation. Skin blood flow decreased to compensate increases in lungs and heart. Blood flow through adipose tissue tended to increase in relation to controls, but was considerably increased in brown adipose tissue (on a weight basis). Discussion. The results suggest that the cafeteria diet-induced changes were related to heat transfer and disposal.
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It is part of: PeerJ, 2016, vol. 4, p. e2302
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ISSN: 2167-8359
Appears in Collections:Articles publicats en revistes (Bioquímica i Biomedicina Molecular)

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