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Title: | Cafeteria diet induce changes in blood flow that are more related with heat dissipation than energy accretion |
Author: | Sabater Martínez, David Agnelli, Silvia Arriarán, Sofía Romero Romero, María del Mar Fernández López, José Antonio Alemany, Marià, 1946- Remesar Betlloch, Xavier |
Keywords: | Circulació sanguínia Rates (Animals de laboratori) Lípids en la nutrició Circulation of the blood Rats as laboratory animals Lipids in human nutrition |
Issue Date: | 3-Aug-2016 |
Publisher: | PeerJ |
Abstract: | Background. A ``cafeteria'' diet is a self-selected high-fat diet, providing an excess of energy, which can induce obesity. Excess of lipids in the diet hampers glucose utilization eliciting insulin resistance, which, further limits amino acid oxidation for energy. Methods. Male Wistar rats were exposed for a month to ``cafeteria'' diet. Rats were cannulated and fluorescent microspheres were used to determine blood flow. Results. Exposure to the cafeteria diet did not change cardiac output, but there was a marked shift in organ irrigation. Skin blood flow decreased to compensate increases in lungs and heart. Blood flow through adipose tissue tended to increase in relation to controls, but was considerably increased in brown adipose tissue (on a weight basis). Discussion. The results suggest that the cafeteria diet-induced changes were related to heat transfer and disposal. |
Note: | Podeu consultar dades primàries associades a l'article a: http://hdl.handle.net/2445/96861 |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.7717/peerj.2302 |
It is part of: | PeerJ, 2016, vol. 4, p. e2302 |
URI: | http://hdl.handle.net/2445/101599 |
Related resource: | http://dx.doi.org/10.7717/peerj.2302 http://hdl.handle.net/2445/96861 |
ISSN: | 2167-8359 |
Appears in Collections: | Articles publicats en revistes (Bioquímica i Biomedicina Molecular) |
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