Please use this identifier to cite or link to this item:
Title: Alteration of interleaflet coupling due to compounds displaying rapid translocation in lipid membranes
Author: Reigada Sanz, Ramon
Keywords: Membranes lipídiques
Dinàmica molecular
Lipid membranes
Molecular dynamics
Issue Date: 6-Sep-2016
Publisher: Nature Publishing Group
Abstract: The spatial coincidence of lipid domains at both layers of the cell membrane is expected to play an important role in many cellular functions. Competition between the surface interleaflet tension and a line hydrophobic mismatch penalty are conjectured to determine the transversal behavior of laterally heterogeneous lipid membranes. Here, by a combination of molecular dynamics simulations, a continuum field theory and kinetic equations, I demonstrate that the presence of small, rapidly translocating molecules residing in the lipid bilayer may alter its transversal behavior by favoring the spatial coincidence of similar lipid phases.
Note: Reproducció del document publicat a:
It is part of: Scientific Reports, 2016, vol. 6, p. 32934
Related resource:
ISSN: 2045-2322
Appears in Collections:Articles publicats en revistes (Ciència dels Materials i Química Física)

Files in This Item:
File Description SizeFormat 
663765.pdf11.62 MBAdobe PDFView/Open

This item is licensed under a Creative Commons License Creative Commons