Please use this identifier to cite or link to this item:
Title: Modifiable risk factors associated with prediabetes in men and women: a cross-sectional analysis of the cohort study in primary health care on the evolution of patients with prediabetes (PREDAPS-Study)
Author: Díaz Redondo, Alicia
Giráldez García, Carolina
Carrillo, Lourdes
Serrano, Rosario
García Soidán, Francisco Javier
Artola, Sara
Franch Nadal, Josep
Díez, Javier
Ezkurra, Patxi
Millaruelo Trillo, José M.
Seguí, Mateu
Sangrós González, Francisco Javier
Martínez Candela, Juan
Muñoz, Pedro
Goday Arnó, Albert
Regidor, Enrique
Keywords: Atenció primària
Factors de risc en les malalties
Primary health care
Risk factors in diseases
Issue Date: 22-Jan-2015
Publisher: BioMed Central
Abstract: Background: Prediabetes is a high-risk state for diabetes development, but little is known about the factors associated with this state. The aim of the study was to identify modifiable risk factors associated with the presence of prediabetes in men and women. Methods: Cohort Study in Primary Health Care on the Evolution of Patients with Prediabetes (PREDAPS-Study) is a prospective study on a cohort of 1184 subjects with prediabetes and another cohort of 838 subjects without glucose metabolism disorders. It is being conducted by 125 general practitioners in Spain. Data for this analysis were collected during the baseline stage in 2012. The modifiable risk factors included were: smoking habit, alcohol consumption, low physical activity, inadequate diet, hypertension, dyslipidemia, and obesity. To assess independent association between each factor and prediabetes, odds ratios (ORs) were estimated using logistic regression models. Results: Abdominal obesity, low plasma levels of high-density lipoprotein cholesterol (HDL-cholesterol), and hypertension were independently associated with the presence of prediabetes in both men and women. After adjusting for all factors, the respective ORs (95% Confidence Intervals) were 1.98 (1.41-2.79), 1.88 (1.23-2.88) and 1.86 (1.39-2.51) for men, and 1.89 (1.36-2.62), 1.58 (1.12-2.23) and 1.44 (1.07-1.92) for women. Also, general obesity was a risk factor in both sexes but did not reach statistical significance among men, after adjusting for all factors. Risky alcohol consumption was a risk factor for prediabetes in men, OR 1.49 (1.00-2.24). Conclusions: Obesity, low HDL-cholesterol levels, and hypertension were modifiable risk factors independently related to the presence of prediabetes in both sexes. The magnitudes of the associations were stronger for men than women. Abdominal obesity in both men and women displayed the strongest association with prediabetes. The findings suggest that there are some differences between men and women, which should be taken into account when implementing specific recommendations to prevent or delay the onset of diabetes in adult population. Keywords: Prediabetes, Modifiable risk factors, Primary health care, Men, Women, Spain
Note: Reproducció del document publicat a:
It is part of: BMC Family Practice, 2015, vol. 16, num. 1, p. 5
Related resource:
ISSN: 1471-2296
Appears in Collections:Articles publicats en revistes (Medicina)

Files in This Item:
File Description SizeFormat 
661210.pdf385.45 kBAdobe PDFView/Open

This item is licensed under a Creative Commons License Creative Commons