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Title: Disability-adjusted-life-years losses in postmenopausal women with osteoporosis: a burden of illness study
Author: Darbà, Josep
Kaskens, Lisette
Pérez Álvarez, Núria
Palacios Ruiz, Lucas Santiago
Neyro, José Luis
Rejas, Javier
Keywords: Menopausa
Anàlisi cost-benefici
Cost effectiveness
Issue Date: Apr-2015
Publisher: BioMed Central
Abstract: To estimate the disability-adjusted life years (DALY) in a nationwide representative sample of postmenopausal women with osteoporosis. The effects of drug-based therapy and risk factors for osteoporotic bone fractures on DALY losses were also explored. DALY were estimated based on participant's clinical characteristics and Health-Related Quality-of-Life (HRQoL) data obtained from a cross-sectional, epidemiological one-visit study (the GINERISK study). The study enrolled postmenopausal women (at least 12-months after their last menstrual period) with osteoporosis, above 18-years old, who attended Spanish outpatient Gynaecology clinics. HRQoL was assessed using the generic SF-12v2 questionnaire, which was used to derive disutility values. Mortality rates were extracted from the Spanish national statistics database. Factors explored to be associated with DALY losses were examined using ANOVA, ANCOVA and MANCOVA models.
Note: Reproducció del document publicat a:
It is part of: BMC Public Health, 2015, vol. 2, num. 15, p. 324-335
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ISSN: 1471-2458
Appears in Collections:Articles publicats en revistes (Economia)

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