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http://hdl.handle.net/2445/104357
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DC Field | Value | Language |
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dc.contributor.author | Merino Montero, Susana | - |
dc.contributor.author | Gonzalez, Victor | - |
dc.contributor.author | Tomàs Magaña, Juan | - |
dc.date.accessioned | 2016-12-01T15:36:43Z | - |
dc.date.available | 2016-12-01T15:36:43Z | - |
dc.date.issued | 2015-07-10 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | http://hdl.handle.net/2445/104357 | - |
dc.description.abstract | The repeat units of heteropolymeric O antigen are synthesized at the cytosolic side of the inner bacterial membrane via the Wzx/Wzy-dependent assembly pathway. After being translocated across the membrane by Wzx, each repeat unit is polymerized by Wzy to form a glycan chain. In this study, we demonstrate the need of the corresponding enzyme trans- ferring the initial HexNAc to undecaprenol phosphate (lipid carrier), together with the corre- sponding O-antigen polymerase (Wzy), to produce the Aeromonas hydrophila O:34- antigen. We suggest, the concerted action of WecA or P enzyme (UDP-HexNAc: polypre- nol-P HexNAc-1-P transferase) and Wzy is involved in the mechanism responsible for the A . hydrophila O-antigen polymerization. | - |
dc.format.extent | 15 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Public Library of Science (PLoS) | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1371/journal.pone.0131905 | - |
dc.relation.ispartof | PLoS One, 2015, vol. 10, num. 7, p. e0131905 | - |
dc.relation.uri | https://doi.org/10.1371/journal.pone.0131905 | - |
dc.rights | cc-by (c) Merino Montero, Susana et al., 2015 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es | - |
dc.source | Articles publicats en revistes (Genètica, Microbiologia i Estadística) | - |
dc.subject.classification | Bacteriòfags | - |
dc.subject.classification | Transferases | - |
dc.subject.classification | Polimerització | - |
dc.subject.other | Bacteriophages | - |
dc.subject.other | Transferases | - |
dc.subject.other | Polymerization | - |
dc.title | The polymerization of Aeromonas hydrophila AH-3 O-antigen LPS: concerted action of WecP and Wzy | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 653853 | - |
dc.date.updated | 2016-12-01T15:36:48Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 26161781 | - |
Appears in Collections: | Articles publicats en revistes (Genètica, Microbiologia i Estadística) |
Files in This Item:
File | Description | Size | Format | |
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653853.pdf | 2.14 MB | Adobe PDF | View/Open |
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