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Title: Effect of Puerperal Infections on Early Neonatal Mortality: A Secondary Analysis of Six Demographic and Health Surveys
Author: Bellizzi, Saverio
Bassat Orellana, Quique
Ali, Mohamed M.
Sobel, Howard L.
Temmerman, Marieen
Keywords: Septicèmia
Malalties neonatals
Mortalitat infantil
Neonatal diseases
Infant mortality
Issue Date: 25-Jan-2017
Publisher: Public Library of Science (PLoS)
Abstract: BACKGROUND: Around 1.5 million annual neonatal deaths occur in the first week of life, and infections represent one of the major causes in developing countries. Neonatal sepsis is often strictly connected to infection of the maternal genital tract during labour. METHODS: The association between signs suggestive of puerperal infection and early neonatal mortality (<7 days of life) was performed using Demographic and Health Surveys (DHS) data of six countries, conducted between 2010 and 2013. The population attributable fraction (PAF) was generated using the estimates on early neonatal mortality of a 1990-2013 systematic analysis for the Global Burden of Disease Study. RESULTS: Signs of puerperal infection ranged from 0.7% in the Philippines to 16.4% in Honduras. Infection was associated with a 2.1 adjusted Risk Ratio (95% CI: 1.4-3.2) of early neonatal mortality. Around five percent of all deaths in the first week of life were attributable to signs suggestive of puerperal infections and varied from 13.9% (95% CI: 1.0-26.6) in Honduras to 3.6% (95% CI: 1.0-8.5) in Indonesia. CONCLUSIONS: Targeted interventions should be addressed to contain the burden of puerperal infections on early neonatal mortality. Consideration of the PAF will help in the discussion of the benefits of antenatal and perinatal measures.
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It is part of: PLoS One, 2017, vol. 12, num. 1, p. e0170856
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ISSN: 1932-6203
Appears in Collections:Articles publicats en revistes (ISGlobal)

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