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Title: Salivary secretory disorders, inducing drugs, and clinical management
Author: Miranda i Rius, Jaume
Brunet i Llobet, Lluís
Lahor i Soler, Eduard
Farré Albaladejo, Magí
Keywords: Saliva
Glàndules salivals
Efectes secundaris dels medicaments
Malalties de les glàndules salivals
Malalties de la boca
Salivary glands
Drug side effects
Salivary gland diseases
Mouth diseases
Issue Date: 22-Sep-2015
Publisher: Ivyspring International
Abstract: Background: Salivary secretory disorders can be the result of a wide range of factors. Their prevalence and negative effects on the patient's quality of life oblige the clinician to confront the issue. Aim: To review the salivary secretory disorders, inducing drugs and their clinical management. Methods: In this article, a literature search of these dysfunctions was conducted with the assistance of a research librarian in the MEDLINE/PubMed Database. Results: Xerostomia, or dry mouth syndrome, can be caused by medication, systemic diseases such as Sjögren's Syndrome, glandular pathologies, and radiotherapy of the head and neck. Treatment of dry mouth is aimed at both minimizing its symptoms and preventing oral complications with the employment of sialogogues and topical acting substances. Sialorrhea and drooling, are mainly due to medication or neurological systemic disease. There are various therapeutic, pharmacologic, and surgical alternatives for its management. The pharmacology of most of the substances employed for the treatment of salivary disorders is well-known. Nevertheless, in some cases a significant improvement in salivary function has not been observed after their administration. Conclusion: At present, there are numerous frequently prescribed drugs whose unwanted effects include some kind of salivary disorder. In addition, the differing pathologic mechanisms, and the great variety of existing treatments hinder the clinical management of these patients. The authors have designed an algorithm to facilitate the decision making process when physicians, oral surgeons, or dentists face these salivary dysfunctions.
Note: Reproducció del document publicat a:
It is part of: International Journal of Medical Sciences, 2015, vol. 12, num. 10, p. 811-824
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ISSN: 1449-1907
Appears in Collections:Articles publicats en revistes (Odontostomatologia)

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