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Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/108026
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dc.contributor.authorAmat Tusón, Mercedes-
dc.contributor.authorPinto, Alexandre-
dc.contributor.authorGriera Farres, Rosa-
dc.contributor.authorBosch Cartes, Joan-
dc.date.accessioned2017-03-07T13:11:15Z-
dc.date.available2017-03-07T13:11:15Z-
dc.date.issued2015-07-21-
dc.identifier.issn0947-6539-
dc.identifier.urihttp://hdl.handle.net/2445/108026-
dc.description.abstractThe marine alkaloids (-)-lepadins A-C and (+)-lepadin D, belonging to two diastereoisomeric series, were synthesized from an (R)-phenylglycinol-derived tricyclic lactam via a common cis-decahydroquinoline intermediate. Crucial aspects of the synthesis are the stereochemical control in the assembly of the cis-decahydroquinoline platform, in the introduction of the C2 methyl and C3 hydroxy substituents, and in the generation of the C5 stereocenter.-
dc.format.extent5 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherWiley-VCH-
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1002/chem.201501909-
dc.relation.ispartofChemistry-A European Journal, 2015, vol. 21, num. 36, p. 12804-12808-
dc.relation.urihttps://doi.org/10.1002/chem.201501909-
dc.rights(c) Wiley-VCH, 2015-
dc.sourceArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)-
dc.subject.classificationAlcaloides-
dc.subject.classificationLactames-
dc.subject.classificationCompostos heterocíclics-
dc.subject.classificationSíntesi asimètrica-
dc.subject.otherAlkaloids-
dc.subject.otherLactams-
dc.subject.otherHeterocyclic compounds-
dc.subject.otherAsymmetric synthesis-
dc.titleEnantioselective synthesis of lepadins A D from a phenylglycinol-derived hydroquinolone lactam-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/acceptedVersion-
dc.identifier.idgrec655588-
dc.date.updated2017-03-07T13:11:15Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
dc.identifier.pmid26202059-
Appears in Collections:Articles publicats en revistes (Institut de Biomedicina (IBUB))
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)

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