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Title: Stereoselectivesynthesis of (-)-lepadins A-C
Author: Amat Tusón, Mercedes
Pinto, Alexandre
Griera Farres, Rosa
Bosch Cartes, Joan
Keywords: Alcaloides
Issue Date: 7-Dec-2013
Publisher: Royal Society of Chemistry
Abstract: A concise synthesis of the marine alkaloids ()-lepadins A-C from a phenylglycinol-derived tricyclic lactam is reported. Key steps from the stereochemical standpoint involve stereoselective cyclocondensation, double bond hydrogenation, oxazolidine opening, hydroboration- oxidation, and Horner-Wadsworth-Emmons reactions.
Note: Versió postprint del document publicat a:
It is part of: Chemical Communications, 2013, vol. 49, num. 94, p. 11032-11034
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ISSN: 1359-7345
Appears in Collections:Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)

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