Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/108263| Title: | A General Synthetic Route to Enantiopure 5-Substituted cis-Decahydroquinolines |
| Author: | Amat Tusón, Mercedes Fabregat, Robert Griera Farres, Rosa Bosch Cartes, Joan |
| Keywords: | Quinolones Síntesi orgànica Lactames Reacció d'oxidació-reducció Quinolone antibacterial agents Organic synthesis Lactams Oxidation-reduction reaction |
| Issue Date: | 20-Feb-2009 |
| Publisher: | American Chemical Society |
| Abstract: | A practical synthetic route to enantiopure 5-substituted cisdecahydroquinolines has been developed, the key steps being a stereoselective cyclocondensation of 2-substituted 6-oxocyclohexenepropionates 2 with (R)-phenylglycinol, the stereoselective hydrogenation of the resulting unsaturated tricyclic lactams, and the stereoselective reductive cleavage of the oxazolidine ring. |
| Note: | Versió postprint del document publicat a: https://doi.org/10.1021/jo802587h. |
| It is part of: | Journal of Organic Chemistry, 2009, vol. 74, num. 4, p. 1794-1797 |
| URI: | http://hdl.handle.net/2445/108263 |
| Related resource: | https://doi.org/10.1021/jo802587h. |
| ISSN: | 0022-3263 |
| Appears in Collections: | Articles publicats en revistes (Institut de Biomedicina (IBUB)) Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 566015.pdf | 207.71 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.