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http://hdl.handle.net/2445/108323
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DC Field | Value | Language |
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dc.contributor.author | Cuervo Requena, Guillermo | - |
dc.contributor.author | Camoez, Mariana | - |
dc.contributor.author | Shaw Perujo, Evelyn | - |
dc.contributor.author | Domínguez Luzón, Ma. Ángeles (María Ángeles) | - |
dc.contributor.author | Gasch, Oriol | - |
dc.contributor.author | Padilla, Belén | - |
dc.contributor.author | Pintado, Vicente | - |
dc.contributor.author | Almirante, Benito | - |
dc.contributor.author | Molina, José | - |
dc.contributor.author | López Medrano, Francisco | - |
dc.contributor.author | Ruiz de Gopegui, Enrique | - |
dc.contributor.author | Martínez Martínez, José Antonio | - |
dc.contributor.author | Bereciartua, Elena | - |
dc.contributor.author | Rodriguez-Lopez, Fernando | - |
dc.contributor.author | Fernandez-Mazarrasa, Carlos | - |
dc.contributor.author | Goenaga Sánchez, Miguel Ángel | - |
dc.contributor.author | Benito Hernández, M. Natividad de | - |
dc.contributor.author | Rodríguez Baño, Jesús | - |
dc.contributor.author | Espejo, Elena | - |
dc.contributor.author | Pujol Rojo, Miquel | - |
dc.contributor.author | Spanish Network for Research in Infectious Diseases (REIPI) | - |
dc.contributor.author | GEIH (Hospital Infection Study Group) | - |
dc.date.accessioned | 2017-03-13T11:09:11Z | - |
dc.date.available | 2017-03-13T11:09:11Z | - |
dc.date.issued | 2015-10-30 | - |
dc.identifier.issn | 1471-2334 | - |
dc.identifier.uri | http://hdl.handle.net/2445/108323 | - |
dc.description.abstract | Background: the aim of the study was to determine clinical and microbiological differences between patients with methicillin-resistant Staphylococcus aureus (MRSA) catheter-related bacteraemia (CRB) undergoing or not undergoing haemodialysis, and to compare outcomes. Methods: prospective multicentre study conducted at 21 Spanish hospitals of patients with MRSA bacteraemia diagnosed between June 2008 and December 2009. Patients with MRSA-CRB were selected. Data of patients on haemodialysis (HD-CRB) and those not on haemodialysis (non-HD-CRB) were compared. Results: among 579 episodes of MRSA bacteraemia, 218 (37.7 %) were CRB. Thirty-four (15.6 %) were HD-CRB and 184 (84.4 %) non-HD-CRB. All HD-CRB patients acquired the infection at dialysis centres, while in 85.3 % of the non-HD-CRB group the infection was nosocomial (p < .001). There were no differences in age, gender or severity of bacteraemia (Pitt score); comorbidities (Charlson score ≥ 4) were higher in the HD-CRB group than in the non-HD-CRB group (73.5 % vs. 46.2 %, p = .003). Although there were no differences in VAN-MIC ≥1.5 mg/L according to microdilution, using the E-test a higher rate of VAN-MIC ≥1.5 mg/L was observed in HD-CRB than in non-HD-CRB patients (63.3 % vs. 44.1 %, p = .051). Vancomycin was more frequently administered in the HD-CRB group than in the non-HD-CRB group (82.3 % vs. 42.4 %, p = <.001) and therefore the appropriate empirical therapy was significantly higher in HD-CRB group (91.2 % vs. 73.9 %, p = .029). There were no differences with regard to catheter removal (79.4 % vs. 84.2 %, p = .555, respectively). No significant differences in mortality rate were observed between both groups (Overall mortality: 11.8 % vs. 27.2 %, p = .081, respectively), but there was a trend towards a higher recurrence rate in HD-CRB group (8.8 % vs. 2.2 %, p = .076). Conclusions: in our multicentre study, ambulatory patients in chronic haemodialysis represented a significant proportion of cases of MRSA catheter-related bacteraemia. Although haemodialysis patients with MRSA catheter-related bacteraemia had significantly more comorbidities and higher proportion of strains with reduced vancomycin susceptibility than non-haemodialysis patients, overall mortality between both groups was similar. | - |
dc.format.extent | 7 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | BioMed Central | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1186/s12879-015-1227-y | - |
dc.relation.ispartof | Bmc Infectious Diseases, 2015, vol. 15, p. 484 | - |
dc.relation.uri | https://doi.org/10.1186/s12879-015-1227-y | - |
dc.rights | cc-by (c) Cuervo Requena, Guillermo et al., 2015 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es | - |
dc.source | Articles publicats en revistes (Patologia i Terapèutica Experimental) | - |
dc.subject.classification | Staphylococcus aureus | - |
dc.subject.classification | Estafilococs | - |
dc.subject.classification | Bacteris | - |
dc.subject.classification | Cateterisme | - |
dc.subject.classification | Hemodiàlisi | - |
dc.subject.other | Staphylococcus aureus | - |
dc.subject.other | Staphylococcus | - |
dc.subject.other | Bacteria | - |
dc.subject.other | Catheterization | - |
dc.subject.other | Hemodialysis | - |
dc.title | Methicillin-resistant Staphylococcus aureus (MRSA) catheter-related bacteraemia in haemodialysis patients | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 657522 | - |
dc.date.updated | 2017-03-13T11:09:11Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 26518487 | - |
Appears in Collections: | Articles publicats en revistes (Medicina) Articles publicats en revistes (Patologia i Terapèutica Experimental) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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