Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/108384
Title: | Asymmetric intermolecular cobalt-catalyzed Pauson-Khand reaction using a p-stereogenic bis-phosphane |
Author: | Orgué Gassol, Sílvia León Serrano, Thierry Riera i Escalé, Antoni Verdaguer i Espaulella, Xavier |
Keywords: | Reacció de Pauson-Khand Catàlisi asimètrica Pauson-Khand reaction Enantioselective catalysis |
Issue Date: | 29-Dec-2014 |
Publisher: | American Chemical Society |
Abstract: | The asymmetric intermolecular and catalytic Pauson-Khand reaction has remained an elusive goal since Khand and Pauson discovered this transformation. Using a novel family of P-stereogenic phosphanes, we developed the first catalytic system with useful levels of enantioselection for the reaction of norbornadiene and trimethylsilylacetylene. The results demonstrate that Co-bisphosphane systems are sufficiently reactive and that they lead to high selectivity in the intermolecular process. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1021/ol503329g |
It is part of: | Organic Letters, 2014, vol. 17, p. 250-253 |
URI: | http://hdl.handle.net/2445/108384 |
Related resource: | https://doi.org/10.1021/ol503329g |
ISSN: | 1523-7060 |
Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) |
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