Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/110002
Title: | P-Stereogenic bisphosphines with a hydrazine backbone: from N-N atropoisomerism to double nitrogen inversion |
Author: | Prades, Amparo Núñez-Pertíñez, Samuel Riera i Escalé, Antoni Verdaguer i Espaulella, Xavier |
Keywords: | Lligands Catàlisi asimètrica Ligands Enantioselective catalysis |
Issue Date: | 31-Mar-2017 |
Publisher: | Royal Society of Chemistry |
Abstract: | The synthesis of P-stereogenic bisphosphine ligands starting from a phosphinous acid chiral synthon and hydrazine is reported. The dialkylation of the hydrazine backbone yielded atropo- and nitrogeninversion isomers which are in slow exchange. The crystallization of one of the isomers allowed us to study the reaction kinetics of the equilibria. The new ligands were tested in the Rh catalysed asymmetric hydrogenation of various benchmark substrates attaining up to 99% ee. |
Note: | Reproducció del document publicat a: https://doi.org/10.1039/C7CC01944K |
It is part of: | Chemical Communications, 2017, vol. 53, p. 4605-4608 |
URI: | http://hdl.handle.net/2445/110002 |
Related resource: | https://doi.org/10.1039/C7CC01944K |
ISSN: | 1359-7345 |
Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
670822.pdf | 1.61 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License