Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/111231
Title: On equivalence and bioequivalence testing.
Author: Ocaña i Rebull, Jordi
Sánchez O., M. Pilar
Sànchez, Àlex (Sànchez Pla)
Sànchez, Àlex (Sànchez Pla) Carrasco Jordan, Josep
Keywords: Ontologies (Informàtica)
Genètica
Models matemàtics
Ontologies (Information retrieval)
Genetics
Mathematical models
Issue Date: 15-Jun-2011
Publisher: Institut d'Estadística de Catalunya
Abstract: Equivalence testing is the natural approach to many statistical problems. First, its main application, bioequivalence testing, is reviewed. The basic concepts of bioequivalence testing (2×2 crossover designs, TOST, interval inclusion principle, etc.) and its problems (TOST biased character, the carryover problem, etc.) are considered. Next, equivalence testing is discussed more generally. Some applications and methods are reviewed and the relation of equivalence testing and distance-based inference is highlighted. A new distance-based method to determine whether two gene lists are equivalent in terms of their annotations in the Gene Ontology illustrates these ideas. We end with a general discussion and some suggestions for future research.
Note: Reproducció del document publicat a: http://www.raco.cat/index.php/SORT/article/view/144068
It is part of: Sort (Statistics and Operations Research Transactions), 2011, vol. 32, num. 2, p. 151-176
URI: http://hdl.handle.net/2445/111231
ISSN: 1696-2281
Appears in Collections:Articles publicats en revistes (Genètica, Microbiologia i Estadística)
Articles publicats en revistes (Fonaments Clínics)

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