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http://hdl.handle.net/2445/112522
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DC Field | Value | Language |
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dc.contributor.author | Sànchez Riera, Lídia | - |
dc.contributor.author | Carnahan, E. | - |
dc.contributor.author | Vos, Theo | - |
dc.contributor.author | Veerman, L. | - |
dc.contributor.author | Norman, R. | - |
dc.contributor.author | Lim, S. S. | - |
dc.contributor.author | Hoy, D. | - |
dc.contributor.author | Smith, E. | - |
dc.contributor.author | Wilson, N. | - |
dc.contributor.author | Nolla Solé, Joan Miquel | - |
dc.contributor.author | Chen, J. S. | - |
dc.contributor.author | Macara, M. | - |
dc.contributor.author | Kamalaraj, N. | - |
dc.contributor.author | Li, Y. | - |
dc.contributor.author | Kok, C. | - |
dc.contributor.author | Santos-Hernández, C. | - |
dc.contributor.author | March, Lyn | - |
dc.date.accessioned | 2017-06-19T07:30:06Z | - |
dc.date.available | 2017-06-19T07:30:06Z | - |
dc.date.issued | 2014-09 | - |
dc.identifier.issn | 0003-4967 | - |
dc.identifier.uri | http://hdl.handle.net/2445/112522 | - |
dc.description.abstract | Introduction: The Global Burden of Disease Study 2010 estimated the worldwide health burden of 291 diseases and injuries and 67 risk factors by calculating disability-adjusted life years (DALYs). Osteoporosis was not considered as a disease, and bone mineral density (BMD) was analysed as a risk factor for fractures, which formed part of the health burden due to falls. Objectives: To calculate (1) the global distribution of BMD, (2) its population attributable fraction (PAF) for fractures and subsequently for falls, and (3) the number of DALYs due to BMD. Methods: A systematic review was performed seeking population-based studies in which BMD was measured by dual-energy X-ray absorptiometry at the femoral neck in people aged 50 years and over. Age- and sex-specific mean ± SD BMD values (g/cm2) were extracted from eligible studies. Comparative risk assessment methodology was used to calculate PAFs of BMD for fractures. The theoretical minimum risk exposure distribution was estimated as the age- and sex-specific 90th centile from the Third National Health and Nutrition Examination Survey (NHANES III). Relative risks of fractures were obtained from a previous meta-analysis. Hospital data were used to calculate the fraction of the health burden of falls that was due to fractures. Results: Global deaths and DALYs attributable to low BMD increased from 103 000 and 3 125 000 in 1990 to 188 000 and 5 216 000 in 2010, respectively. The percentage of low BMD in the total global burden almost doubled from 1990 (0.12%) to 2010 (0.21%). Around one-third of falls-related deaths were attributable to low BMD. Conclusions: Low BMD is responsible for a growing global health burden, only partially representative of the real burden of osteoporosis. | - |
dc.format.extent | 11 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | BMJ Publishing Group | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1136/annrheumdis-2013-204320 | - |
dc.relation.ispartof | Annals of the Rheumatic Diseases, 2014, vol. 73, num. 9, p. 1635-1645 | - |
dc.relation.uri | https://doi.org/10.1136/annrheumdis-2013-204320 | - |
dc.rights | (c) BMJ Publishing Group, 2014 | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | Osteoporosi | - |
dc.subject.classification | Malalties dels ossos | - |
dc.subject.classification | Densitometria òssia | - |
dc.subject.classification | Salut pública | - |
dc.subject.classification | Fractures | - |
dc.subject.classification | Ressenyes sistemàtiques (Investigació mèdica) | - |
dc.subject.other | Osteoporosis | - |
dc.subject.other | Bone diseases | - |
dc.subject.other | Bone densitometry | - |
dc.subject.other | Public health | - |
dc.subject.other | Fractures | - |
dc.subject.other | Systematic reviews (Medical research) | - |
dc.title | The global burden attributable to low bone mineral density | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 639710 | - |
dc.date.updated | 2017-06-19T07:30:06Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 24692584 | - |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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639710.pdf | 4.29 MB | Adobe PDF | View/Open |
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