Please use this identifier to cite or link to this item:
Title: Evidence of association of the NLRP1 gene with giant cell arteritis
Author: Serrano, Aurora
Carmona, F. David
Castañeda, Santos
Solans, Roser
Hernández Rodríguez, José
Cid Xutglà, M. Cinta
Prieto González, Sergio
Miranda-Filloy, José A.
Rodríguez-Rodríguez, Luis
Morado, Inmaculada C.
Gómez Vaquero, Carmen
Blanco, Ricardo
Sopeña, Bernardo
Ortego Centeno, Norberto
Unzurrunzaga, Ainhoa
Marí-Alfonso, Begoña
Sánchez-Martin, Julio
García-Villanueva, María Jesús
Hidalgo-Conde, Ana
Pazzola, Giulia
Boiardi, Luigi
Salvarani, Carlo
González-Gay, Miguel A.
Martín, Javier
Keywords: Arteritis de cèl·lules gegants
Polimorfisme genètic
Giant cell arteritis
Genetic polymorphisms
Issue Date: Apr-2013
Publisher: BMJ Publishing Group
Abstract: Recent studies have focused attention on the involvement of NLRP1 to confer susceptibility for extended autoimmune/inflammatory disorders, being considered a common risk factor in autoimmunity. NLRP1 provides a scaffold for the assembly of the inflammasome that activates caspases 1 and 5, required for processing and activation of the proinflammatory cytokines interleukin 1β (IL-1β), IL-18 and IL-33 and promoting inflammation.
Note: Reproducció del document publicat a:
It is part of: Annals of the Rheumatic Diseases, 2013, vol. 72, num. 4, p. 628-630
Related resource:
ISSN: 0003-4967
Appears in Collections:Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)
Articles publicats en revistes (Ciències Clíniques)
Articles publicats en revistes (Medicina)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Files in This Item:
File Description SizeFormat 
641076.pdf103.02 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.