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Title: Combined dielectrophoresis and impedance systems for bacteria analysis in microfluidic on-chip platforms
Author: Páez-Avilés, Cristina
Juanola, Esteve
Punter Villagrasa, Jaime
Moral, Beatriz del
Homs Corbera, Antoni
Colomer i Farrarons, Jordi
Miribel-Català, Pere Ll. (Pere Lluís)
Samitier i Martí, Josep
Keywords: Impedància (Electricitat)
Sistema monoxip
Impedance (Electricity)
Systems on a chip
Issue Date: 16-Sep-2016
Publisher: MDPI
Abstract: Bacteria concentration and detection is time-consuming in regular microbiology procedures aimed to facilitate the detection and analysis of these cells at very low concentrations. Traditional methods are effective but often require several days to complete. This scenario results in low bioanalytical and diagnostic methodologies with associated increased costs and complexity. In recent years, the exploitation of the intrinsic electrical properties of cells has emerged as an appealing alternative approach for concentrating and detecting bacteria. The combination of dielectrophoresis (DEP) and impedance analysis (IA) in microfluidic on-chip platforms could be key to develop rapid, accurate, portable, simple-to-use and cost-effective microfluidic devices with a promising impact in medicine, public health, agricultural, food control and environmental areas. The present document reviews recent DEP and IA combined approaches and the latest relevant improvements focusing on bacteria concentration and detection, including selectivity, sensitivity, detection time, and conductivity variation enhancements. Furthermore, this review analyses future trends and challenges which need to be addressed in order to successfully commercialize these platforms resulting in an adequate social return of public-funded investments.
Note: Reproducció del document publicat a:
It is part of: Sensors, 2016, vol. 16, num. 9, p. 1514
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ISSN: 1424-8220
Appears in Collections:Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC))
Articles publicats en revistes (Electrònica)

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