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DC Field | Value | Language |
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dc.contributor.author | Shi, Ting | - |
dc.contributor.author | McAllister, David A. | - |
dc.contributor.author | O'Brien, Katherine L. | - |
dc.contributor.author | Simoes, Eric A. F. | - |
dc.contributor.author | Madhi, Shabir A. | - |
dc.contributor.author | Gessner, Bradford D. | - |
dc.contributor.author | Polack, Fernando P. | - |
dc.contributor.author | Balsells, Evelyn | - |
dc.contributor.author | Acácio, Sozinho | - |
dc.contributor.author | Aguayo, Claudia | - |
dc.contributor.author | Alassani, Issifou | - |
dc.contributor.author | Moyes, Jocelyn | - |
dc.contributor.author | Nymadawa, Pagbajabyn | - |
dc.contributor.author | Da Costa Oliveira, Maria Tereza | - |
dc.contributor.author | Oshitani, Histoshi | - |
dc.contributor.author | Pandey, Nitin | - |
dc.contributor.author | Paranhos-Baccala, Gláucia | - |
dc.contributor.author | Phillips, Lia N. | - |
dc.contributor.author | Scott, J. Anthony G. | - |
dc.contributor.author | Sanchez Picot, Valentina | - |
dc.contributor.author | Shen, Kunling | - |
dc.contributor.author | Schweiger, Brunhilde | - |
dc.contributor.author | Rahman, Mustafizur | - |
dc.contributor.author | Rakoto-Andrianarivelo, Mala | - |
dc.contributor.author | Rasmussen, Zeba A. | - |
dc.contributor.author | Rath, Barbara A. | - |
dc.contributor.author | Robinson, Annick | - |
dc.contributor.author | Romero, Candice | - |
dc.contributor.author | Russomando, Graciela | - |
dc.contributor.author | Salimi, Vahid | - |
dc.contributor.author | Sawatwong, Pongpun | - |
dc.contributor.author | Seidenberg, Phil | - |
dc.contributor.author | Sotomayor, Viviana | - |
dc.contributor.author | Singleton, Rosalyn | - |
dc.contributor.author | Scheltema, Nienke | - |
dc.contributor.author | Strand, Tor A. | - |
dc.contributor.author | Sutanto, Agustinos | - |
dc.contributor.author | Sylla, Mariam | - |
dc.contributor.author | Tapia, Milagritos D. | - |
dc.contributor.author | Thamthitiwat, Somsak | - |
dc.contributor.author | Ali, Asad | - |
dc.contributor.author | Thomas, Elizabeth D. | - |
dc.contributor.author | Nair, Harish | - |
dc.contributor.author | RSV Global Epidemiology Network | - |
dc.contributor.author | Tokarz, Rafal | - |
dc.contributor.author | Turner, Claudia | - |
dc.contributor.author | Venter, Marietjie | - |
dc.contributor.author | Waicharoen, Sunthareeya | - |
dc.contributor.author | Wang, Jianwei | - |
dc.contributor.author | Watthanaworawit, Wanitda | - |
dc.contributor.author | Yoshida, Lay-Myint | - |
dc.contributor.author | Yu, Hongjie | - |
dc.contributor.author | Zar, Heather J. | - |
dc.contributor.author | Antonio, Martin | - |
dc.contributor.author | Awori, Juliet O. | - |
dc.contributor.author | Awasthi, Shally | - |
dc.contributor.author | Campbell, Harry | - |
dc.contributor.author | Azziz-Baumgartner, Eduardo | - |
dc.contributor.author | Baggett, Henry C. | - |
dc.contributor.author | Baillie, Vicky | - |
dc.contributor.author | Balmaseda, Angel | - |
dc.contributor.author | Barahona, Alfredo | - |
dc.contributor.author | Basnet, Sudha | - |
dc.contributor.author | Bassat Orellana, Quique | - |
dc.contributor.author | Chipeta, James | - |
dc.contributor.author | Chadha, Mandeep | - |
dc.contributor.author | Basualdo, Wilma | - |
dc.contributor.author | Bigogo, Godfrey | - |
dc.contributor.author | Bont, Louis J. | - |
dc.contributor.author | Breiman, Robert F. | - |
dc.contributor.author | Brooks, Abdullah W. | - |
dc.contributor.author | Broor, Shobha | - |
dc.contributor.author | Bruce, Nigel | - |
dc.contributor.author | Bruden, Dana | - |
dc.contributor.author | Buchy, Philippe | - |
dc.contributor.author | Campbell, Stuart | - |
dc.contributor.author | Clara, Wilfrido | - |
dc.contributor.author | Chou, Monidarin | - |
dc.contributor.author | Carosone-Link, Phyllis | - |
dc.contributor.author | Cohen, Cheryl | - |
dc.contributor.author | Cuellar, Elizabeth de | - |
dc.contributor.author | Dang, Duc-Anh | - |
dc.contributor.author | Dash-Yandag, Budragchaagiin | - |
dc.contributor.author | Deloria-Knoll, Maria | - |
dc.contributor.author | Dherani, Mukesh | - |
dc.contributor.author | Eap, Tekchheng | - |
dc.contributor.author | Ebruke, Bernard E. | - |
dc.contributor.author | Howie, Stephe R. C. | - |
dc.contributor.author | Echavarria, Marcela | - |
dc.contributor.author | de Freitas Lazaro Emediato, Carla Cecília | - |
dc.contributor.author | Fasce, Rodrigo A. | - |
dc.contributor.author | Feikin, Daniel R. | - |
dc.contributor.author | Feng, Luzhao | - |
dc.contributor.author | Gentile, Angela | - |
dc.contributor.author | Gordon, Aubree | - |
dc.contributor.author | Goswami, Doli | - |
dc.contributor.author | Goyet, Sophie | - |
dc.contributor.author | Homaira, Nusrat | - |
dc.contributor.author | Jara, Jorge | - |
dc.contributor.author | Groome, Michelle | - |
dc.contributor.author | Halasa, Natasha | - |
dc.contributor.author | Jroundi, Imane | - |
dc.contributor.author | Kartasasmita, Cissy B. | - |
dc.contributor.author | Khuri-Bulos, Najwa | - |
dc.contributor.author | Kotloff, Karen L. | - |
dc.contributor.author | Krishnan, Anand | - |
dc.contributor.author | Libster, Romina | - |
dc.contributor.author | Munywoki, Patrick | - |
dc.contributor.author | Lopez, Olga | - |
dc.contributor.author | Nicol, Mark P. | - |
dc.contributor.author | Lucero, Marilla G. | - |
dc.contributor.author | Lucion, Florencia | - |
dc.contributor.author | Lupisan, Socorro P. | - |
dc.contributor.author | Marcone, Debora N. | - |
dc.contributor.author | McCracken, John P. | - |
dc.contributor.author | Mejia, Mario | - |
dc.contributor.author | Moisi, Jennifer C. | - |
dc.contributor.author | Montgomery, Joel M. | - |
dc.contributor.author | Moore, David P. | - |
dc.contributor.author | Mutyara, Kuswandewi | - |
dc.contributor.author | Nokes, D. James | - |
dc.contributor.author | Moraleda Redecilla, Cinta | - |
dc.date.accessioned | 2017-07-21T11:42:42Z | - |
dc.date.available | 2017-07-21T11:42:42Z | - |
dc.date.issued | 2017-07-06 | - |
dc.identifier.issn | 0140-6736 | - |
dc.identifier.uri | http://hdl.handle.net/2445/114188 | - |
dc.description.abstract | BACKGROUND: We have previously estimated that respiratory syncytial virus (RSV) was associated with 22% of all episodes of (severe) acute lower respiratory infection (ALRI) resulting in 55 000 to 199 000 deaths in children younger than 5 years in 2005. In the past 5 years, major research activity on RSV has yielded substantial new data from developing countries. With a considerably expanded dataset from a large international collaboration, we aimed to estimate the global incidence, hospital admission rate, and mortality from RSV-ALRI episodes in young children in 2015. METHODS: We estimated the incidence and hospital admission rate of RSV-associated ALRI (RSV-ALRI) in children younger than 5 years stratified by age and World Bank income regions from a systematic review of studies published between Jan 1, 1995, and Dec 31, 2016, and unpublished data from 76 high quality population-based studies. We estimated the RSV-ALRI incidence for 132 developing countries using a risk factor-based model and 2015 population estimates. We estimated the in-hospital RSV-ALRI mortality by combining in-hospital case fatality ratios with hospital admission estimates from hospital-based (published and unpublished) studies. We also estimated overall RSV-ALRI mortality by identifying studies reporting monthly data for ALRI mortality in the community and RSV activity. FINDINGS: We estimated that globally in 2015, 33.1 million (uncertainty range [UR] 21.6-50.3) episodes of RSV-ALRI, resulted in about 3.2 million (2.7-3.8) hospital admissions, and 59 600 (48 000-74 500) in-hospital deaths in children younger than 5 years. In children younger than 6 months, 1.4 million (UR 1.2-1.7) hospital admissions, and 27 300 (UR 20 700-36 200) in-hospital deaths were due to RSV-ALRI. We also estimated that the overall RSV-ALRI mortality could be as high as 118 200 (UR 94 600-149 400). Incidence and mortality varied substantially from year to year in any given population. INTERPRETATION: Globally, RSV is a common cause of childhood ALRI and a major cause of hospital admissions in young children, resulting in a substantial burden on health-care services. About 45% of hospital admissions and in-hospital deaths due to RSV-ALRI occur in children younger than 6 months. An effective maternal RSV vaccine or monoclonal antibody could have a substantial effect on disease burden in this age group. FUNDING: The Bill & Melinda Gates Foundation. | - |
dc.format.extent | 13 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier | - |
dc.relation.isformatof | Reproducció del document publicat a: http://dx.doi.org/10.1016/S0140-6736(17)30938-8 | - |
dc.relation.ispartof | Lancet, 2017, (17) 30938-8 | - |
dc.relation.uri | http://dx.doi.org/10.1016/S0140-6736(17)30938-8 | - |
dc.rights | cc by (c) Shi, Ting et al., 2017 | - |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | - |
dc.source | Articles publicats en revistes (ISGlobal) | - |
dc.subject.classification | Infeccions respiratòries | - |
dc.subject.classification | Virologia mèdica | - |
dc.subject.other | Respiratory infections | - |
dc.subject.other | Medical virology | - |
dc.title | Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.date.updated | 2017-07-19T18:00:07Z | - |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/H2020/116019/EU//RESCEU | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 28689664 | - |
Appears in Collections: | Articles publicats en revistes (ISGlobal) Publicacions de projectes de recerca finançats per la UE |
Files in This Item:
File | Description | Size | Format | |
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shi2017_2614.pdf | 1.63 MB | Adobe PDF | View/Open |
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