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Title: | Updated global estimates of respiratory mortality in adults >/=30Years of age attributable to long-term ozone exposure |
Author: | Malley, Christopher S. Henze, Daven K. Kuylenstierna, Johan C. I. Vallack, Harry W. Davila, Yanko Anenberg, Susan C. Turner, Michelle C. Ashmore, Mike R. |
Keywords: | Ozó Mortalitat Ozone Mortality |
Issue Date: | 28-Aug-2017 |
Publisher: | National Institute of Environmental Health Science |
Abstract: | BACKGROUND: Relative risk estimates for long-term ozone (O3) exposure and respiratory mortality from the American Cancer Society Cancer Prevention Study II (ACS CPS-II) cohort have been used to estimate global O3-attributable mortality in adults. Updated relative risk estimates are now available for the same cohort based on an expanded study population with longer follow-up. OBJECTIVES: We estimated the global burden and spatial distribution of respiratory mortality attributable to long-term O3 exposure in adults >/=30y of age using updated effect estimates from the ACS CPS-II cohort. METHODS: We used GEOS-Chem simulations (2x2.5 masculine grid resolution) to estimate annual O3 exposures, and estimated total respiratory deaths in 2010 that were attributable to long-term annual O3 exposure based on the updated relative risk estimates and minimum risk thresholds set at the minimum or fifth percentile of O3 exposure in the most recent CPS-II analysis. These estimates were compared with attributable mortality based on the earlier CPS-II analysis, using 6-mo average exposures and risk thresholds corresponding to the minimum or fifth percentile of O3 exposure in the earlier study population. RESULTS: We estimated 1.04-1.23 million respiratory deaths in adults attributable to O3 exposures using the updated relative risk estimate and exposure parameters, compared with 0.40-0.55 million respiratory deaths attributable to O3 exposures based on the earlier CPS-II risk estimate and parameters. Increases in estimated attributable mortality were larger in northern India, southeast China, and Pakistan than in Europe, eastern United States, and northeast China. CONCLUSIONS: These findings suggest that the potential magnitude of health benefits of air quality policies targeting O3, health co-benefits of climate mitigation policies, and health implications of climate change-driven changes in O3 concentrations, are larger than previously thought. https://doi.org/10.1289/EHP1390. |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.1289/EHP1390 |
It is part of: | Environmental Health Perspectives, 2017, vol. 125, num. 8, p. 087021 |
URI: | http://hdl.handle.net/2445/115590 |
Related resource: | http://dx.doi.org/10.1289/EHP1390 |
ISSN: | 0091-6765 |
Appears in Collections: | Articles publicats en revistes (ISGlobal) |
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malley2017_2678.pdf | 1.63 MB | Adobe PDF | View/Open |
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