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Title: | Mass spectometry imaging: optimization of sample preparation and metabolite identification through MS/MS |
Other Titles: | Espectrometria de masses d’imatge: optimització de preparacions de mostra i identificació de metabòlits per MS/MS |
Author: | Fernández Navas, Nora |
Director/Tutor: | Juan Capdevila, Anna de Bedia Girbés, Carmen |
Keywords: | Metabòlits Espectrometria de masses Desorció-ionització amb làser assistit per matriu Cèl·lules i teixits vegetals Treballs de fi de grau Metabolites Mass spectrometry Matrix-assisted laser desorption-ionization Plant cells and tissues Bachelor's theses |
Issue Date: | Jun-2017 |
Abstract: | Metabolomics consists in the study of small molecules called metabolites which are present in living organisms. These low mass compounds are the ultimate answer to perturbations produced in the organism. Therefore, their quantification and identification lead to a reading out of the cellular state. In order to obtain this information, analytical techniques are employed. The use of mass spectrometry imaging allows to obtain structural and spatial distribution information of the studied sample. Two important points are considered when this analysis is undergone: tissue sample preparation and metabolites identification. The present work is focused to improve these difficulties in various plant tissues utilizing Matrix Assisted Laser Desorption Ionization (MALDI) imaging as instrument. This project has been carried out at the Institut de Diagnosi Ambiental i Estudis de l’Aigua (IDAEA) laboratories of Consell Superior d’Investigacions Científiques (CSIC) |
Note: | Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2017, Tutores: Anna de Juan Capdevila, Carmen Bedia Girbes |
URI: | http://hdl.handle.net/2445/116055 |
Appears in Collections: | Treballs Finals de Grau (TFG) - Química |
Files in This Item:
File | Description | Size | Format | |
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Fernández Navas Nora.pdf | 2.13 MB | Adobe PDF | View/Open |
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