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Title: | The effectiveness of influenza vaccination in the elderly in Spain in two influenza seasons: a multicenter case-control study |
Author: | Domínguez García, Àngela Soldevila, Núria Toledo Zavaleta, Diana Isabel Godoy i García, Pere Espejo, Elena Fernández, M.A. Mayoral, José María Castilla, Jesús Egurrola, Mikel Tamames, Sonia Astray, Jenaro Morales Suárez-Varela, María Torner Gràcia, Núria |
Keywords: | Grip Vacunació Persones grans Espanya Influenza Vaccination Older people Spain |
Issue Date: | 24-Aug-2017 |
Publisher: | European Centre for Disease Prevention and Control (ECDC) |
Abstract: | Influenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged ≥ 65 years in Spain. A multicentre case-control study was conducted in 20 Spanish hospitals during 2013/14 and 2014/15. Patients aged ≥ 65 years who were hospitalised with laboratory-confirmed influenza were matched with controls according to sex, age and date of hospitalisation. Adjusted vaccine effectiveness (VE) was calculated by multivariate conditional logistic regression. A total of 728 cases and 1,826 matched controls were included in the study. Overall VE was 36% (95% confidence interval (CI): 22-47). VE was 51% (95% CI: 15-71) in patients without high-risk medical conditions and 30% (95% CI: 14-44) in patients with them. VE was 39% (95% CI: 20-53) in patients aged 65-79 years and 34% (95% CI: 11-51) in patients aged ≥ 80 years, and was greater against the influenza A(H1N1)pdm09 subtype than the A(H3N2) subtype. Influenza vaccination was effective in preventing hospitalisations of elderly individuals. |
Note: | Reproducció del document publicat a: https://doi.org/10.2807/1560-7917.ES.2017.22.34.30602 |
It is part of: | Eurosurveillance, 2017, vol. 22, num. 34, p. 30602 |
URI: | http://hdl.handle.net/2445/116702 |
Related resource: | https://doi.org/10.2807/1560-7917.ES.2017.22.34.30602 |
ISSN: | 1560-7917 |
Appears in Collections: | Articles publicats en revistes (Medicina) |
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