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http://hdl.handle.net/2445/120251
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DC Field | Value | Language |
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dc.contributor.author | McGrath, John J. | - |
dc.contributor.author | McLaughlin, K. A. | - |
dc.contributor.author | Saha, Sukanta | - |
dc.contributor.author | Aguilar-Gaxiola, Sergio | - |
dc.contributor.author | Al-Hamzawi, Ali Obaid | - |
dc.contributor.author | Alonso, Jordi | - |
dc.contributor.author | Bruffaerts, Ronny | - |
dc.contributor.author | Girolamo, Giovanni de | - |
dc.contributor.author | Jonge, Peter de | - |
dc.contributor.author | Esan, O. | - |
dc.contributor.author | Florescu, Silvia E. | - |
dc.contributor.author | Gureje, Oye | - |
dc.contributor.author | Haro Abad, Josep Maria | - |
dc.contributor.author | Hu, Chiyi | - |
dc.contributor.author | Karam, Elie Georges | - |
dc.contributor.author | Kovess-Masfety, Viviane | - |
dc.contributor.author | Lee, Soon Yeun | - |
dc.contributor.author | Lepine, Jean Pierre | - |
dc.contributor.author | Lim, Carmen C. W. | - |
dc.contributor.author | Medina Mora, Maria Elena | - |
dc.contributor.author | Mneimneh, Z. | - |
dc.contributor.author | Pennell, Beth-Ellen | - |
dc.contributor.author | Piazza, Marina | - |
dc.contributor.author | Posada Villa, José | - |
dc.contributor.author | Sampson, Nancy A. | - |
dc.contributor.author | Viana, Maria Carmen | - |
dc.contributor.author | Xavier, Miguel | - |
dc.contributor.author | Bromet, Evelyn J. | - |
dc.contributor.author | Kendler, Kenneth S. | - |
dc.contributor.author | Kessler, Ronald C. | - |
dc.date.accessioned | 2018-02-26T11:20:15Z | - |
dc.date.available | 2018-02-26T11:20:15Z | - |
dc.date.issued | 2017-01-09 | - |
dc.identifier.issn | 0033-2917 | - |
dc.identifier.uri | http://hdl.handle.net/2445/120251 | - |
dc.description.abstract | Although there is robust evidence linking childhood adversities (CAs) and an increased risk for psychotic experiences (PEs), little is known about whether these associations vary across the life-course and whether mental disorders that emerge prior to PEs explain these associations. METHOD: We assessed CAs, PEs and DSM-IV mental disorders in 23 998 adults in the WHO World Mental Health Surveys. Discrete-time survival analysis was used to investigate the associations between CAs and PEs, and the influence of mental disorders on these associations using multivariate logistic models. RESULTS: Exposure to CAs was common, and those who experienced any CAs had increased odds of later PEs [odds ratio (OR) 2.3, 95% confidence interval (CI) 1.9-2.6]. CAs reflecting maladaptive family functioning (MFF), including abuse, neglect, and parent maladjustment, exhibited the strongest associations with PE onset in all life-course stages. Sexual abuse exhibited a strong association with PE onset during childhood (OR 8.5, 95% CI 3.6-20.2), whereas Other CA types were associated with PE onset in adolescence. Associations of other CAs with PEs disappeared in adolescence after adjustment for prior-onset mental disorders. The population attributable risk proportion (PARP) for PEs associated with all CAs was 31% (24% for MFF). CONCLUSIONS: Exposure to CAs is associated with PE onset throughout the life-course, although sexual abuse is most strongly associated with childhood-onset PEs. The presence of mental disorders prior to the onset of PEs does not fully explain these associations. The large PARPs suggest that preventing CAs could lead to a meaningful reduction in PEs in the population. | - |
dc.format.extent | 26 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Cambridge University Press | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1017/S0033291716003263 | - |
dc.relation.ispartof | Psychological Medicine, 2017, vol. 47, num. 7 | - |
dc.relation.uri | https://doi.org/10.1017/S0033291716003263 | - |
dc.rights | (c) Cambridge University Press, 2017 | - |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | Malalties mentals | - |
dc.subject.classification | Infants | - |
dc.subject.other | Mental illness | - |
dc.subject.other | Children | - |
dc.title | The association between childhood adversities and subsequent first onset of psychotic experiences: a cross-national analysis of 23 998 respondents from 17 countries | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 667890 | - |
dc.date.updated | 2018-02-26T11:20:15Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 28065209 | - |
Appears in Collections: | Articles publicats en revistes (Medicina) |
Files in This Item:
File | Description | Size | Format | |
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667890.pdf | 417.75 kB | Adobe PDF | View/Open |
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