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dc.contributor.authorBujanda, Luis-
dc.contributor.authorSarasqueta, Cristina-
dc.contributor.authorLanas, Angel-
dc.contributor.authorQuintero, Enrique-
dc.contributor.authorCubiella, Joaquín-
dc.contributor.authorHernandez, V.-
dc.contributor.authorMorillas, Juan D.-
dc.contributor.authorPerez-Fernández, T.-
dc.contributor.authorSalas, D.-
dc.contributor.authorAndreu, Montserrat-
dc.contributor.authorCarballo, F.-
dc.contributor.authorBessa i Caserras, Xavier-
dc.contributor.authorPortillo, I.-
dc.contributor.authorJover, Rodrigo-
dc.contributor.authorBalaguer Prunés, Francesc-
dc.contributor.authorCosme, Angel-
dc.contributor.authorCastells Garangou, Antoni-
dc.description.abstractBackground: We aimed to evaluate whether oral anticoagulants (OACs) alter faecal immunochemical test (FIT) performance in average-risk colorectal cancer (CRC) screening. Methods: Individuals aged 50-69 years were invited to receive one FIT sample (cutoff 75 ng ml-1) between November 2008 and June 2011. Results: Faecal immunochemical test was positive in 9.3% (21 out of 224) of users of OAC and 6.2% (365 out of 5821) of non-users (P-trend ¼ 0.07). The positive predictive value (PPV) for advanced neoplasia (AN) in non-users was 50.4% vs 47.6% in users (odds ratio, 0.70; 95% CI, 0.3-1.8; P ¼ 0.5). The PPV for AN in OAC more antiplatelets (aspirin or clopidogrel) was 75% (odds ratio, 2; 95% CI, 0.4-10.8; P ¼ 0.4). Conclusions: Oral anticoagulant did not significantly modify the PPV for AN in this population-based colorectal screening program. The detection rate of advanced adenoma was higher in the combination OAC more antiplatelets.-
dc.format.extent4 p.-
dc.publisherCancer Research UK-
dc.relation.isformatofReproducció del document publicat a:
dc.relation.ispartofBritish Journal of Cancer, 2014, vol. 110, num. 5, p. 1334-1337-
dc.rightscc-by-nc-sa (c) Bujanda, Luis et al., 2014-
dc.subject.classificationCàncer colorectal-
dc.subject.classificationAnticoagulants (Medicina)-
dc.subject.classificationEstudi de casos-
dc.subject.otherColorectal cancer-
dc.subject.otherAnticoagulants (Medicine)-
dc.subject.otherCase studies-
dc.titleEffect of oral anticoagulants on the outcome of faecal immunochemical test-
Appears in Collections:Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)
Articles publicats en revistes (Medicina)

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