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Title: Factors associated with hospitalization in bronchiectasis exacerbations: a one-year follow-up study
Author: Menéndez, Rosario
Méndez, Raúl
Polverino, Eva
Rosales Mayor, Edmundo
Amara Elori, Isabel
Reyes, Soledad
Posadas, Tomás
Fernández Barat, Laia
Torres Martí, Antoni
Keywords: Malalties pulmonars obstructives cròniques
Factors de risc en les malalties
Vacuna antipneumocòccica
Chronic obstructive pulmonary diseases
Risk factors in diseases
Pneumococcal vaccine
Issue Date: 30-Sep-2017
Publisher: BioMed Central
Abstract: Background: Bronchiectasis (BE) is a chronic structural lung disease with frequent exacerbations, some of which require hospital admission though no clear associated factors have been identified. We aimed to evaluate factors associated with hospitalization due to exacerbations during a 1-year follow-up period. Methods: A prospective observational study was performed in patients recruited from specialized BE clinics. We considered all exacerbations diagnosed and treated with antibiotics during a follow-up period of 1 year. The protocol recorded baseline variables, usual treatments, Bronchiectasis Severity Index (BSI) and FACED scores, comorbid conditions and prior hospitalizations. Results: Two hundred and 65 patients were recruited, of whom 162 required hospital admission during the follow-up period. Independent risk factors for hospital admission were age, previous hospitalization due to BE, use of proton pump inhibitors, heart failure, FACED and BSI, whereas pneumococcal vaccination was a protective factor. The area under the receiver operator characteristic curve (AUC) was 0.799 for BSI model was 0.799, and 0.813 for FACED model. Conclusions: Previous hospitalization, use of proton pump inhibitors, heart failure along with BSI or FACED scores is associated factors for developing exacerbations that require hospitalization. Pneumococcal vaccination was protective. This information may be useful for the design of preventive strategies and more intensive follow-up plans.
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It is part of: Respiratory Research, 2017, vol. 18, num. 176
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ISSN: 1465-993X
Appears in Collections:Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

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