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Title: Waist-to-height ratio and cardiovascular risk factors in elderly individuals at high cardiovascular risk
Author: Guasch-Ferré, Marta
Bulló, Mònica
Martínez-González, Miguel Ángel, 1957-
Corella Piquer, Dolores
Estruch Riba, Ramon
Covas Planells, María Isabel
Arós, Fernando
Wärnberg, Julia
Fiol Sala, Miguel
Lapetra, José
Muñoz, Miguel Ángel
Serra Majem, Lluís
Pintó Sala, Xavier
Babio, Nancy
Díaz López, Andrés
Salas Salvadó, Jordi
Keywords: Malalties cardiovasculars
Persones grans
Cardiovascular diseases
Older people
Issue Date: 14-Aug-2012
Publisher: Public Library of Science (PLoS)
Abstract: Introduction Several anthropometric measurements have been associated with cardiovascular disease, type-2 diabetes mellitus and other cardiovascular risk conditions, such as hypertension or metabolic syndrome. Waist-to-height-ratio has been proposed as a useful tool for assessing abdominal obesity, correcting other measurements for the height of the individual. We compared the ability of several anthropometric measurements to predict the presence of type-2 diabetes, hyperglycemia, hypertension, atherogenic dyslipidemia or metabolic syndrome. Materials and Methods In our cross-sectional analyses we included 7447 Spanish individuals at high cardiovascular risk, men aged 55-80 years and women aged 60-80 years, from the PREDIMED study. Logistic regression models were fitted to evaluate the odds ratio of presenting each cardiovascular risk factor according to various anthropometric measures. The areas under the receiver-operating characteristic curve (AUC) were used to compare the predictive ability of these measurements. Results In this relatively homogeneous cohort with 48.6% of type-2 diabetic individuals, the great majority of the studied anthropometric parameters were significantly and positively associated with the cardiovascular risk factors. No association was found between BMI and body weight and diabetes mellitus. The AUCs for the waist-to-height ratio and waist circumference were significantly higher than the AUCs for BMI or weight for type-2 diabetes, hyperglycemia, atherogenic dyslipidemia and metabolic syndrome. Conversely, BMI was the strongest predictor of hypertension. Conclusions We concluded that measures of abdominal obesity showed higher discriminative ability for diabetes mellitus, high fasting plasma glucose, atherogenic dyslipidemia and metabolic syndrome than BMI or weight in a large cohort of elderly Mediterranean individuals at high cardiovascular risk. No significant differences were found between the predictive abilities of waist-to-height ratio and waist circumference on the metabolic disease.
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It is part of: PLoS One, 2012, vol. 7, num. 8, p. e43275
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ISSN: 1932-6203
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Articles publicats en revistes (Medicina)

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