Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/125071
Title: Initiation and propagation of activity in neuronal cultures under connectivity alterations
Author: Herrera Carrillo, Jose Arnau
Director/Tutor: Soriano i Fradera, Jordi
Keywords: Xarxes neuronals (Neurobiologia)
Soroll
Treballs de fi de grau
Neural networks (Neurobiology)
Noise
Bachelor's thesis
Issue Date: Jun-2018
Abstract: Activity in living neuronal networks is governed by complex laws that are still poorly understood. To advance in this quest, we study the initiation and propagation of activity fronts in in vitro neuronal networks. We consider two major experiments in which we modify the connectivity of the network. In a first one, we physically cut a region of the culture. I a second one we apply a drug that changes the connectivity of the network. In both experiments, we determine the velocity of the activity fronts, their timing and the point of origin. We frame our results in the context of the noise focusing phenomena, a mechanism that explains the initiation of activity in terms of network connectivity, neuronal dynamics, and amplification of noise
Note: Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2018, Tutor: Jordi Soriano Fradera
URI: http://hdl.handle.net/2445/125071
Appears in Collections:Treballs Finals de Grau (TFG) - Física

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