Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/125277
Title: | Night shift work and stomach cancer risk in the MCC-Spain study |
Author: | Gyarmati, Georgina Turner, Michelle C. Castaño-Vinyals, Gemma Espinosa Cardiel, Ana Papantoniou, Kyriaki Alguacil, Juan Costas, Laura Pérez Gómez, Beatriz Martín Sánchez, Vicente Ardanaz, Eva Moreno Aguado, Víctor Gómez Acebo, Inés Fernández Tardón, Guillermo Villanueva Ballester, Vicent Capelo Álvarez, Rocío Chirlaque, María Dolores Santibáñez, Miguel Pollán, Marina Aragonès Sanz, Núria Kogevinas, Manolis |
Keywords: | Estòmac Càncer Espanya Stomach Cancer Spain |
Issue Date: | 16-Jun-2016 |
Publisher: | BMJ Publishing Group |
Abstract: | OBJECTIVES: Night shift work has been classified as a probable human carcinogen by the International Agency for Research on Cancer, based on experimental studies and limited evidence on human breast cancer risk. Evidence at other cancer sites is scarce. We evaluated the association between night shift work and stomach cancer risk in a population-based case-control study. METHODS: A total of 374 incident stomach adenocarcinoma cases and 2481 population controls were included from the MCC-Spain study. Detailed data on lifetime night shift work were collected including permanent and rotating shifts, and their cumulative duration (years). Adjusted unconditional logistic regression models were used in analysis. RESULTS: A total of 25.7% of cases and 22.5% of controls reported ever being a night shift worker. There was a weak positive, non-significant association between ever having had worked for at least 1 year in permanent night shifts and stomach cancer risk compared to never having worked night shifts (OR=1.2, 95% CI 0.9 to 1.8). However, there was an inverse 'U' shaped relationship with cumulative duration of permanent night shifts, with the highest risk observed in the intermediate duration category (OR 10-20 years=2.0, 95% CI 1.1 to 3.6) (p for trend=0.19). There was no association with ever having had worked in rotating night shifts (OR=0.9, 95% CI 0.6 to 1.2) and no trend according to cumulative duration (p for trend=0.68). CONCLUSION: We found no clear evidence concerning an association between night shift work and stomach cancer risk. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1136/oemed-2016-103597 |
It is part of: | Occupational and Environmental Medicine, 2016, vol. 73, num. 8, p. 520-527 |
URI: | http://hdl.handle.net/2445/125277 |
Related resource: | https://doi.org/10.1136/oemed-2016-103597 |
ISSN: | 1351-0711 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) Articles publicats en revistes (ISGlobal) Articles publicats en revistes (Ciències Clíniques) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
665140.pdf | 270.21 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.