Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/125277
Title: Night shift work and stomach cancer risk in the MCC-Spain study
Author: Gyarmati, Georgina
Turner, Michelle C.
Castaño-Vinyals, Gemma
Espinosa Cardiel, Ana
Papantoniou, Kyriaki
Alguacil, Juan
Costas, Laura
Pérez Gómez, Beatriz
Martín Sánchez, Vicente
Ardanaz, Eva
Moreno Aguado, Víctor
Gómez Acebo, Inés
Fernández-Tardon, Guillermo
Villanueva Ballester, Vicent
Capelo, Rocio
Chirlaque, María Dolores
Santibáñez, Miguel
Pollán, Marina
Aragonès Sanz, Núria
Kogevinas, Manolis
Keywords: Estómac
Càncer
Espanya
Stomach
Cancer
Spain
Issue Date: 16-Jun-2016
Publisher: BMJ Publishing Group
Abstract: OBJECTIVES: Night shift work has been classified as a probable human carcinogen by the International Agency for Research on Cancer, based on experimental studies and limited evidence on human breast cancer risk. Evidence at other cancer sites is scarce. We evaluated the association between night shift work and stomach cancer risk in a population-based case-control study. METHODS: A total of 374 incident stomach adenocarcinoma cases and 2481 population controls were included from the MCC-Spain study. Detailed data on lifetime night shift work were collected including permanent and rotating shifts, and their cumulative duration (years). Adjusted unconditional logistic regression models were used in analysis. RESULTS: A total of 25.7% of cases and 22.5% of controls reported ever being a night shift worker. There was a weak positive, non-significant association between ever having had worked for at least 1 year in permanent night shifts and stomach cancer risk compared to never having worked night shifts (OR=1.2, 95% CI 0.9 to 1.8). However, there was an inverse 'U' shaped relationship with cumulative duration of permanent night shifts, with the highest risk observed in the intermediate duration category (OR 10-20 years=2.0, 95% CI 1.1 to 3.6) (p for trend=0.19). There was no association with ever having had worked in rotating night shifts (OR=0.9, 95% CI 0.6 to 1.2) and no trend according to cumulative duration (p for trend=0.68). CONCLUSION: We found no clear evidence concerning an association between night shift work and stomach cancer risk.
Note: Versió postprint del document publicat a: https://doi.org/10.1136/oemed-2016-103597
It is part of: Occupational and Environmental Medicine, 2016, vol. 73, num. 8, p. 520-527
URI: http://hdl.handle.net/2445/125277
Related resource: https://doi.org/10.1136/oemed-2016-103597
ISSN: 1351-0711
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Articles publicats en revistes (ISGlobal)
Articles publicats en revistes (Ciències Clíniques)

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