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dc.contributor.authorAbbas, Sascha-
dc.contributor.authorLinseisen, Jakob-
dc.contributor.authorRohrmann, Sabine-
dc.contributor.authorBeulens, Joline W. J.-
dc.contributor.authorBuijsse, Brian-
dc.contributor.authorAmiano, Pilar-
dc.contributor.authorArdanaz, Eva-
dc.contributor.authorBalkau, Beverley-
dc.contributor.authorBoeing, Heiner-
dc.contributor.authorClavel-Chapelon, Françoise-
dc.contributor.authorFagherazzi, Guy-
dc.contributor.authorFranks, Paul W.-
dc.contributor.authorGavrila, Diana-
dc.contributor.authorGrioni, Sara-
dc.contributor.authorKaaks, Rudolf-
dc.contributor.authorKey, Timothy J.-
dc.contributor.authorKhaw, Kay-Tee-
dc.contributor.authorKühn, Tilman-
dc.contributor.authorMattiello, Amalia-
dc.contributor.authorMolina Montes, Esther-
dc.contributor.authorNilsson, Peter M.-
dc.contributor.authorOvervad, Kim-
dc.contributor.authorQuirós, J. Ramón-
dc.contributor.authorRolandsson, Olov-
dc.contributor.authorSacerdote, Carlotta-
dc.contributor.authorSaieva, Calogero-
dc.contributor.authorSlimani, Nadia-
dc.contributor.authorSluijs, Ivonne-
dc.contributor.authorSpijkerman, Annemieke M. W.-
dc.contributor.authorTjønneland, Anne-
dc.contributor.authorTumino, Rosario-
dc.contributor.authorvan der A, Daphne L.-
dc.contributor.authorZamora-Ros, Raul-
dc.contributor.authorSharp, Stephen J.-
dc.contributor.authorLangenberg, Claudia-
dc.contributor.authorForouhi, Nita G.-
dc.contributor.authorRiboli, Elio-
dc.contributor.authorWareham, Nicholas J.-
dc.description.abstractBACKGROUND/OBJECTIVES: Prospective cohort studies have indicated that serum vitamin D levels are inversely related to risk of type 2 diabetes. However, such studies cannot determine the source of vitamin D. Therefore, we examined the association of dietary vitamin D intake with incident type 2 diabetes within the European Prospective Investigation into Cancer and Nutrition (EPIC)-InterAct study in a heterogeneous European population including eight countries with large geographical variation. SUBJECTS/METHODS: Using a case-cohort design, 11 245 incident cases of type 2 diabetes and a representative subcohort (N = 15 798) were included in the analyses. Hazard ratios (HR) and 95% confidence intervals (CIs) for type 2 diabetes were calculated using a Prentice-weighted Cox regression adjusted for potential confounders. Twenty-four-hour diet-recall data from a subsample (N = 2347) were used to calibrate habitual intake data derived from dietary questionnaires. RESULTS: Median follow-up time was 10.8 years. Dietary vitamin D intake was not significantly associated with the risk of type 2 diabetes. HR and 95% CIs for the highest compared to the lowest quintile of uncalibrated vitamin D intake was 1.09 (0.97-1.22) (P-trend = 0.17). No associations were observed in a sex-specific analysis. The overall pooled effect (HR (95% CI)) using the continuous calibrated variable was 1.00 (0.97-1.03) per increase of 1 mg/day dietary vitamin D. CONCLUSIONS: This observational study does not support an association between higher dietary vitamin D intake and type 2 diabetes incidence. This result has to be interpreted in light of the limited contribution of dietary vitamin D on the overall vitamin D status of a person.-
dc.format.extent7 p.-
dc.publisherNature Publishing Group-
dc.relation.isformatofVersió postprint del document publicat a:
dc.relation.ispartofEuropean Journal of Clinical Nutrition, 2014, vol. 68, num. 2, p. 196-202-
dc.rights(c) Abbas et al., 2014-
dc.subject.classificationDiabetis no-insulinodependent-
dc.subject.otherNon-insulin-dependent diabetes-
dc.titleDietary vitamin D intake and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition: the EPIC-InterAct study-
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)

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