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http://hdl.handle.net/2445/126283
Title: | On the expanding terminology in the GPCR field: The meaning of receptor mosaics and receptor heteromers |
Author: | Agnati, Luigi F. Guidolin, Diego Vilardaga, Jean Pierre Ciruela Alférez, Francisco Fuxe, Kjell |
Keywords: | Oligòmers Desenvolupament de medicaments Oligomers Drug development |
Issue Date: | Oct-2010 |
Publisher: | Taylor and Francis |
Abstract: | The oligomerization of G protein-coupled receptors (GPCRs) is a fact that deserves further attention as increases both the complexity and diversity of the receptor-mediated signal transduction, thus enriching the cell signaling. Consequently, in the present review we tackle among others the problems concerning the terminology used to describe aspects surrounding the GPCRs oligomerization phenomenon. Therefore, the theoretical implications of the GPCR oligomerization will be briefly discussed together with possible implications of this phenomenon especially for new strategies in drug development. |
Note: | Versió postprint del document publicat a: https://doi.org/10.3109/10799891003786226 |
It is part of: | Journal Of Receptors And Signal Transduction, 2010, vol. 30, num. 5, p. 287-303 |
URI: | http://hdl.handle.net/2445/126283 |
Related resource: | https://doi.org/10.3109/10799891003786226 |
ISSN: | 1079-9893 |
Appears in Collections: | Articles publicats en revistes (Patologia i Terapèutica Experimental) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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599126.pdf | 2.82 MB | Adobe PDF | View/Open |
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