Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/126468
Title: Macronutrient Composition of the Diet and Prospective Weight Change in Participants of the EPIC-PANACEA Study
Author: Vergnaud, Anne-Claire
Norat, Teresa
Mouw, Traci
Romaguera, Dora
May, Anne M.
Bueno de Mesquita, H. Bas
van der A, Daphne
Agudo, Antonio
Wareham, Nicholas J.
Khaw, Kay-Tee
Romieu, Isabelle
Freisling, Heinz
Slimani, Nadia
Perquier, Florence
Boutron-Ruault, Marie-Christine
Clavel-Chapelon, Françoise
Palli, Domenico
Berrino, Franco
Mattiello, Amalia
Tumino, Rosario
Ricceri, Fulvio
Rodriguez, Laudina
Molina Montes, Esther
Amiano, Pilar
Barricarte, Aurelio
Chirlaque, María Dolores
Crowe, Francesca L.
Orfanos, Philippos
Naska, Androniki
Trichopoulou, Antonia
Teucher, Birgit
Kaaks, Rudolf
Boeing, Heiner
Buijsse, Brian
Johansson, Ingegerd
Hallmans, Göran
Drake, Isabel
Sonestedt, Emily
Jakobsen, Marianne Uhre
Overvad, Kim
Tjønneland, Anne
Halkjær, Jytte
Skeie, Guri
Braaten, Tonje
Lund, Eiliv
Riboli, Elio
Peeters, Petra H. M.
Keywords: Obesitat mòrbida
Dieta
Morbid obesity
Diet
Issue Date: 5-Mar-2013
Publisher: Public Library of Science (PLoS)
Abstract: Background: The effect of the macronutrient composition of the usual diet on long term weight maintenance remains controversial. Methods: 373,803 subjects aged 25-70 years were recruited in 10 European countries (1992-2000) in the PANACEA project of the EPIC cohort. Diet was assessed at baseline using country-specific validated questionnaires and weight and height were measured at baseline and self-reported at follow-up in most centers. The association between weight change after 5 years of follow-up and the iso-energetic replacement of 5% of energy from one macronutrient by 5% of energy from another macronutrient was assessed using multivariate linear mixed-models. The risk of becoming overweight or obese after 5 years was investigated using multivariate Poisson regressions stratified according to initial Body Mass Index. Results: A higher proportion of energy from fat at the expense of carbohydrates was not significantly associated with weight change after 5 years. However, a higher proportion of energy from protein at the expense of fat was positively associated with weight gain. A higher proportion of energy from protein at the expense of carbohydrates was also positively associated with weight gain, especially when carbohydrates were rich in fibre. The association between percentage of energy from protein and weight change was slightly stronger in overweight participants, former smokers, participants >= 60 years old, participants underreporting their energy intake and participants with a prudent dietary pattern. Compared to diets with no more than 14% of energy from protein, diets with more than 22% of energy from protein were associated with a 23-24% higher risk of becoming overweight or obese in normal weight and overweight subjects at baseline. Conclusion: Our results show that participants consuming an amount of protein above the protein intake recommended by the American Diabetes Association may experience a higher risk of becoming overweight or obese during adult life.
Note: Reproducció del document publicat a: https://doi.org/10.1371/journal.pone.0057300
It is part of: PLoS One, 2013, vol. 8, num. 3, p. e57300
URI: http://hdl.handle.net/2445/126468
Related resource: https://doi.org/10.1371/journal.pone.0057300
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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