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http://hdl.handle.net/2445/127666
Title: | Chasing the elusive hold-up time from an LFER approach |
Author: | Subirats i Vila, Xavier Justicia, Althea Rosés Pascual, Martí |
Keywords: | Cromatografia de líquids Nitrosamines Termodinàmica Liquid chromatography Nitrosoamines Thermodynamics |
Issue Date: | 8-Aug-2018 |
Publisher: | Elsevier B.V. |
Abstract: | A homologous series approach derived from the Abraham's solvation model was developed for the determination of hold-up times. Firstly, it was tested from reversed-phase liquid chromatography data obtained in the literature involving several series of homologues, followed by its application in a polymeric zwitterionic HILIC column using two different homologous series (n-alkyl benzenes and n-alkyl phenones). Acetonitrile and methanol were selected as organic modifiers in a composition range between 80% and 100% in volume. Results obtained for both series were consistent, and hold-up times were found to be strongly dependent on the water content and the organic modifier nature of the mobile phase. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1016/j.chroma.2018.08.017 |
It is part of: | Journal of Chromatography A, 2018, vol. 1571, p. 176-184 |
URI: | http://hdl.handle.net/2445/127666 |
Related resource: | https://doi.org/10.1016/j.chroma.2018.08.017 |
ISSN: | 0021-9673 |
Appears in Collections: | Articles publicats en revistes (Enginyeria Química i Química Analítica) |
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