Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/127864
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dc.contributor.authorMorán Badenas, María del Carmen-
dc.contributor.authorVinardell Martínez-Hidalgo, Ma. Pilar-
dc.contributor.authorInfante, M. Rosa-
dc.contributor.authorMiguel, M. Graça-
dc.contributor.authorLindman, Björn, 1942--
dc.date.accessioned2019-02-04T15:16:57Z-
dc.date.available2019-02-04T15:16:57Z-
dc.date.issued2014-03-
dc.identifier.issn0001-8686-
dc.identifier.urihttp://hdl.handle.net/2445/127864-
dc.description.abstractA general understanding of interactions between DNA and oppositely charged compounds forms the basis for developing novel DNA-based materials, including gel particles. The association strength, which is altered by varying the chemical structure of the cationic cosolute, determines the spatial homogeneity of the gelation process, creating DNA reservoir devices and DNA matrix devices that can be designed to release either single- (ssDNA) or double-stranded (dsDNA). This review covers recent developments on the topic of DNA gel particles formed in water-water emulsion-type interfaces. The degree of DNA entrapment, particle morphology, swelling/dissolution behaviour and DNA release responses are discussed as a function of the nature of the cationic agent used. On the basis of designing DNA gel particles for therapeutic purposes, recent studies on the determination of the surface hydrophobicity, the haemolytic and the cytotoxic assessments of the obtained DNA gel particles have been also reported.-
dc.format.extent17 p.-
dc.format.mimetypeapplication/pdf-
dc.language.isoeng-
dc.publisherElsevier-
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1016/j.cis.2013.09.002-
dc.relation.ispartofAdvances in Colloid and Interface Science, 2014, vol. 205, p. 240-256-
dc.relation.urihttps://doi.org/10.1016/j.cis.2013.09.002-
dc.rights(c) Elsevier, 2014-
dc.subject.classificationADN-
dc.subject.classificationAgents tensioactius-
dc.subject.classificationMaterials nanoestructurats-
dc.subject.classificationPolímers-
dc.subject.classificationSistemes d'alliberament de medicaments-
dc.subject.classificationNanopartícules-
dc.subject.classificationCol·loides en medicina-
dc.subject.otherDNA-
dc.subject.otherSurface active agents-
dc.subject.otherNanostructured materials-
dc.subject.otherPolymers-
dc.subject.otherDrug delivery systems-
dc.subject.otherNanoparticles-
dc.subject.otherColloids in medicine-
dc.titleDNA gel particles: An overview-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/acceptedVersion-
dc.identifier.idgrec628249-
dc.date.updated2019-02-04T15:16:57Z-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess-
Appears in Collections:Articles publicats en revistes (Bioquímica i Fisiologia)

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