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Title: Magnetic nanoparticles: From diagnosis to therapy
Author: Busquets i Viñas, Ma. Antonia
Estelrich i Latràs, Joan
Keywords: Nanopartícules
Issue Date: 2018
Publisher: Research Signpost
Abstract: Magnetic nanoparticles have proven to be promising theranostic agents, namely tools for therapy and diagnosis. Among them, superparamagnetic iron oxide nanoparticles (SPIONs) highlight for their biocompatibility and reduced toxicity. Here, we describe the synthesis and characterization of SPIONs by co-precipitation of ferric and ferrous salts under mild conditions. These particles were able to accumulate in inflamed areas fact that was increased upon the application of an external magnetic field. Resonance magnetic imaging studies have shown their suitability as negative contrast agents for diagnosis. In addition, hybrid nanoparticles were obtained by incorporating the above described SPIONs into liposomes or nanoemulsions. The findings have confirmed the high potential of these systems for biomedical applications.
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It is part of: Recent Advances in Pharmaceutical Sciences VIII, 2018, Research Signpost. Editors: Diego Muñoz-Torrero, Yolanda Cajal and Joan Maria Llobet. ISBN: 978-81-308-0579-5. Chapter 1, p. 1-18
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Appears in Collections:Llibres / Capítols de llibre (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)
Llibres / Capítols de llibre (Farmacologia, Toxicologia i Química Terapèutica)

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