Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/128109
Title: | Development of hybrid compounds to tackle Alzheimer’s disease |
Author: | Muñoz-Torrero López-Ibarra, Diego Pérez Areales, Francisco Javier |
Keywords: | Desenvolupament de medicaments Malaltia d'Alzheimer Química farmacèutica Drug development Alzheimer's disease Pharmaceutical chemistry |
Issue Date: | 2018 |
Publisher: | Research Signpost |
Abstract: | Alzheimer’s disease (AD) is the main neurodegenerative disorder worldwide. Its pathogenesis involves a network where various mechanisms are interconnected. This complex pathological network makes it extremely challenging to find an efficacious treatment. Herein, we give an overview on the design of the so-called multi-target-directed ligands, i.e. compounds that concurrently hit several key pathogenic factors within the network, as a realistic option to tackle AD, with a particular emphasis on some structural classes of multitarget hybrids recently developed in our group. |
Note: | Podeu consultar el llibre complet a: http://hdl.handle.net/2445/128014 |
Note: | Reproducció del capítol del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=287 |
It is part of: | Recent Advances in Pharmaceutical Sciences VIII, 2018, Research Signpost. Editors: Diego Muñoz-Torrero, Yolanda Cajal and Joan Maria Llobet. ISBN: 978-81-308-0579-5. Chapter 3, p. 43-58 |
URI: | http://hdl.handle.net/2445/128109 |
Related resource: | http://hdl.handle.net/2445/128014 http://hdl.handle.net/2445/115549 |
Appears in Collections: | Llibres / Capítols de llibre (Farmacologia, Toxicologia i Química Terapèutica) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
T_1548756197munoz 3.pdf | 1.5 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License