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Title: Cross-national epidemiology of panic disorder and panic attacks in the world mental health surveys
Author: Jonge, Peter de
Roest, Annelieke M.
Lim, Carmen C. W.
Florescu, Silvia E.
Bromet, Evelyn
Stein, Dan
Harris, Meredith
Nakov, Vladimir
Caldas de Almeida, Jose Miguel
Levinson, Daphna
Al-Hamzawi, Ali Obaid
Haro Abad, Josep Maria
Viana, Maria Carmen
Borgs, Gui
Neill, Siobhan O'
Girolamo, Giovanni de
Demyttenaere, Koen
Gureje, Oye
Iwata, Noboru
Lee, Sing
Hu, Chiyi
Karam, Aimee
Moskalewicz, Jacek
Kovess-Masfety, Viviane
Navarro-Mateu, Fernando
Oakley Browne, Mark
Piazza, Maria
Posada Villa, José
Torres, Yolanda
ten Have, Margreet L.
Kessler, Ronald C.
Scott, Kate M.
Keywords: Atacs de pànic
Trastorns de pànic
Panic attacks
Panic disorders
Issue Date: 1-Dec-2016
Publisher: Wiley
Abstract: CONTEXT: The scarcity of cross-national reports and the changes in Diagnostic and Statistical Manual version 5 (DSM-5) regarding panic disorder (PD) and panic attacks (PAs) call for new epidemiological data on PD and PAs and its subtypes in the general population. OBJECTIVE: To present representative data about the cross-national epidemiology of PD and PAs in accordance with DSM-5 definitions. DESIGN AND SETTING: Nationally representative cross-sectional surveys using the World Health Organization Composite International Diagnostic Interview version 3.0. PARTICIPANTS: Respondents (n = 142,949) from 25 high, middle, and lower-middle income countries across the world aged 18 years or older. MAIN OUTCOME MEASURES: PD and presence of single and recurrent PAs. RESULTS: Lifetime prevalence of PAs was 13.2% (SE 0.1%). Among persons that ever had a PA, the majority had recurrent PAs (66.5%; SE 0.5%), while only 12.8% fulfilled DSM-5 criteria for PD. Recurrent PAs were associated with a subsequent onset of a variety of mental disorders (OR 2.0; 95% CI 1.8-2.2) and their course (OR 1.3; 95% CI 1.2-2.4) whereas single PAs were not (OR 1.1; 95% CI 0.9-1.3 and OR 0.7; 95% CI 0.6-0.8). Cross-national lifetime prevalence estimates were 1.7% (SE 0.0%) for PD with a median age of onset of 32 (IQR 20-47). Some 80.4% of persons with lifetime PD had a lifetime comorbid mental disorder. CONCLUSIONS: We extended previous epidemiological data to a cross-national context. The presence of recurrent PAs in particular is associated with subsequent onset and course of mental disorders beyond agoraphobia and PD, and might serve as a generic risk marker for psychopathology.
Note: Versió postprint del document publicat a:
It is part of: Depression and Anxiety, 2016, vol. 33, num. 12, p. 1155-1177
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ISSN: 1091-4269
Appears in Collections:Articles publicats en revistes (Medicina)

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