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http://hdl.handle.net/2445/128361
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DC Field | Value | Language |
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dc.contributor.author | Saladrigas, Mar | - |
dc.contributor.author | Loren, Guillem | - |
dc.contributor.author | Bonjoch i Sesé, Josep | - |
dc.contributor.author | Bradshaw, Ben | - |
dc.date.accessioned | 2019-02-18T10:21:11Z | - |
dc.date.available | 2019-11-30T06:10:19Z | - |
dc.date.issued | 2018-11 | - |
dc.identifier.issn | 2155-5435 | - |
dc.identifier.uri | http://hdl.handle.net/2445/128361 | - |
dc.description.abstract | A methodology for the coupling of alkenes with aldehyde- or ketone-derived Cbz-hydrazones to form a new C−C bond through a radical process is described. The sequence comprises an initial in situ generation of a putative iron hydride followed by a hydrogen atom transfer to an alkene, a coupling with a hydrazone, and a final reduction of the nitrogen-centered radical. Hydrogenation of the obtained hydrazines renders amines, including valuable tert-alkyl amines. KEYWORDS: HAT, iron catalysis, α-tert-amines, C−C bond formation, radical processes, synthetic methods | - |
dc.format.extent | 5 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | American Chemical Society | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1021/acscatal.8b03794 | - |
dc.relation.ispartof | ACS Catalysis, 2018, vol. 8, p. 11699-11703 | - |
dc.relation.uri | https://doi.org/10.1021/acscatal.8b03794 | - |
dc.rights | (c) American Chemical Society , 2018 | - |
dc.source | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) | - |
dc.subject.classification | Amines | - |
dc.subject.classification | Alquens | - |
dc.subject.classification | Catàlisi | - |
dc.subject.classification | Enllaços químics | - |
dc.subject.classification | Química orgànica | - |
dc.subject.other | Amines | - |
dc.subject.other | Alkenes | - |
dc.subject.other | Catalysis | - |
dc.subject.other | Chemical bonds | - |
dc.subject.other | Organic chemistry | - |
dc.title | Hydrogen Atom Transfer (HAT)-Triggered Iron-Catalyzed Intra- and Intermolecular Coupling of Alkenes with Hydrazones: Access to Complex Amines | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 683227 | - |
dc.date.updated | 2019-02-18T10:21:11Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
Appears in Collections: | Articles publicats en revistes (Institut de Biomedicina (IBUB)) Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) |
Files in This Item:
File | Description | Size | Format | |
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683227.pdf | 385.52 kB | Adobe PDF | View/Open |
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