Please use this identifier to cite or link to this item:
Title: Acute flaccid paralysis (AFP) surveillance: challenges and opportunities from 18 years' experience, Spain, 1998 to 2015
Author: Masa Calles, Josefa
Torner Gràcia, Núria
López Perea, Noemí
Torres de Mier, María V.
Fernández Martínez, Beatriz
Cabrerizo, María
Gallardo García, Virtudes
Malo, Carmen
Margolles, Mario
Portell, Margarita
Abadía, Natividad
Blasco, Aniceto
García Hernández, Sara
Marcos, Henar
Rabella, Núria
Marín, Celia
Fuentes, Amelia
Losada, Isabel
García Gutiérrez, Juan
Nieto, Alba
García Ortúzar, Visitación
García Cenoz, Manuel
Arteagoitia, José María
Blanco Martínez, Ángela
Rivas, Ana
Castrillejo, Daniel
Spanish Afp Surveillance Working Group
Keywords: Poliomielitis
Malalties infeccioses
Salut pública
Communicable diseases
Public health
Issue Date: 22-Nov-2018
Publisher: European Centre for Disease Prevention and Control (ECDC)
Abstract: Acute flaccid paralysis (AFP) surveillance is key for global polio eradication. It allows detecting poliovirus (PV) reintroductions from endemic countries. This study describes AFP surveillance in Spain from 1998 to 2015. During this time, 678 AFP cases were reported to the Spanish National Surveillance Network. The mean notification rate was 0.58 AFP cases/100,000 population under 15 years old (range: 0.45/100,000-0.78/100,000). Two periods (P) are described: P1 (1998-2006) with the AFP notification rate ranging from 0.66/100,000 to 0.78/100,000, peaking in 2001 (0.84/100,000); and P2 (2007-2015) when the AFP rate ranged from 0.43/100,000 to 0.57/100,000, with the lowest rate in 2009 (0.31/100,000). No poliomyelitis cases were caused by wild PV infections, although two Sabin-like PVs and one imported vaccine-derived PV-2 were detected. Overall, 23 (3.4%) cases met the hot case definition. Most cases were clinically diagnosed with Guillain-Barré syndrome (76.9%; 504/655). The adequate stool collection rate ranged from 33.3% (7/21) to 72.5% (29/40). The annual proportion of AFP cases with non-polio enterovirus findings varied widely across the study period. AFP surveillance with laboratory testing for non-polio enteroviruses must be maintained and enhanced both to monitor polio eradication and to establish sensitive surveillance for prompt detection of other enteroviruses causing serious symptoms.
Note: Reproducció del document publicat a:
It is part of: Eurosurveillance, 2018, vol. 23, num. 47
Related resource:
ISSN: 1560-7917
Appears in Collections:Articles publicats en revistes (Medicina)

Files in This Item:
File Description SizeFormat 
686179.pdf344.81 kBAdobe PDFView/Open

This item is licensed under a Creative Commons License Creative Commons