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http://hdl.handle.net/2445/132064
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DC Field | Value | Language |
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dc.contributor.author | Benito, Eva | - |
dc.contributor.author | Cabanelas, Nuno | - |
dc.contributor.author | Nuñez-Garcia, Marta | - |
dc.contributor.author | Alarcón, Francisco | - |
dc.contributor.author | Figueras i Ventura, Rosa M. | - |
dc.contributor.author | Soto Iglesias, David | - |
dc.contributor.author | Guasch i Casany, Eduard | - |
dc.contributor.author | Prat González, Susanna | - |
dc.contributor.author | Perea Palazón, Rosario Jesús | - |
dc.contributor.author | Borràs, Roger | - |
dc.contributor.author | Butakoff, Constantine | - |
dc.contributor.author | Camara, Oscar | - |
dc.contributor.author | Bisbal, Felipe | - |
dc.contributor.author | Arbelo, Elena | - |
dc.contributor.author | Tolosana, José M. (José María) | - |
dc.contributor.author | Brugada Terradellas, Josep, 1958- | - |
dc.contributor.author | Berruezo Sánchez, Antonio | - |
dc.contributor.author | Mont Girbau, Lluís | - |
dc.date.accessioned | 2019-04-11T12:47:31Z | - |
dc.date.available | 2019-12-31T06:10:16Z | - |
dc.date.issued | 2018-12-01 | - |
dc.identifier.issn | 1099-5129 | - |
dc.identifier.uri | http://hdl.handle.net/2445/132064 | - |
dc.description.abstract | Aims: Left atrial (LA) fibrosis can be identified by late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) in patients with atrial fibrillation (AF). However, there is limited information about anatomical fibrosis distribution in the left atrium. The aim is to determine whether there is a preferential spatial distribution of fibrosis in the left atrium in patients with AF. Methods and results: A 3-Tesla LGE-CMR was performed in 113 consecutive patients referred for AF ablation. Images were post-processed and analysed using ADAS-AF software (Galgo Medical), which allows fibrosis identification in 3D colour-coded shells. A regional semiautomatic LA parcellation software was used to divide the atrial wall into 12 segments: 1-4, posterior wall; 5-6, floor; 7, septal wall; 8-11, anterior wall; 12, lateral wall. The presence and amount of fibrosis in each segment was obtained for analysis. After exclusions for artefacts and insufficient image quality, 76 LGE-MRI images (68%) were suitable for fibrosis analysis. Segments 3 and 5, closest to the left inferior pulmonary vein, had significantly higher fibrosis (40.42% ± 23.96 and 25.82% ± 21.24, respectively; P < 0.001), compared with other segments. Segments 8 and 10 in the anterior wall contained the lowest fibrosis (2.54% ± 5.78 and 3.82% ± 11.59, respectively; P < 0.001). Age >60 years was significantly associated with increased LA fibrosis [95% confidence interval (CI) 0.19-8.39, P = 0.04] and persistent AF approached significance (95% CI -0.19% to 7.83%, P = 0.08). Conclusion: In patients with AF, the fibrotic area is preferentially located at the posterior wall and floor around the antrum of the left inferior pulmonary vein. Age >60 years was associated with increased fibrosis. | - |
dc.format.extent | 31 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Oxford University Press | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1093/europace/euy095 | - |
dc.relation.ispartof | Europace, 2018, vol. 20, num. 12, p. 1959-1965 | - |
dc.relation.uri | https://doi.org/10.1093/europace/euy095 | - |
dc.rights | (c) Benito, Eva et al., 2018 | - |
dc.source | Articles publicats en revistes (Medicina) | - |
dc.subject.classification | Ressonància magnètica | - |
dc.subject.classification | Malalties del cor | - |
dc.subject.classification | Fibril·lació auricular | - |
dc.subject.other | Magnetic resonance | - |
dc.subject.other | Heart diseases | - |
dc.subject.other | Atrial fibrillation | - |
dc.title | Preferential regional distribution of atrial fibrosis in posterior wall around left inferior pulmonary vein as identified by late gadolinium enhancement cardíac magnetic resonance in patients with atrial fibrillation | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 685960 | - |
dc.date.updated | 2019-04-11T12:47:31Z | - |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/H2020/633196/EU//CATCH ME | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 29860416 | - |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Medicina) |
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File | Description | Size | Format | |
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685960.pdf | 1.69 MB | Adobe PDF | View/Open |
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