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Title: Amino-acid-based surfactants: New antimicrobial agents
Author: Pinazo Gassol, Aurora
Manresa Presas, Ma. Ángeles (María Ángeles)
Marqués Villavecchia, Ana M.
Bustelo, M.
Espuny Tomás, Ma. José (María José)
Pérez Muñoz, Lourdes
Keywords: Agents tensioactius
Tecnologia farmacèutica
Fórmules magistrals
Agents antiinfecciosos
Toxicitat dels medicaments
Surface active agents
Pharmaceutical technology
Medical formularies
Anti-infective agents
Amino acids
Drug toxicity
Issue Date: Feb-2016
Publisher: Elsevier
Abstract: The rapid increase of drug resistant bacteria makes necessary the development of new antimicrobial agents. Synthetic amino acid-based surfactants constitute a promising alternative to conventional antimicrobial compounds given that they can be prepared from renewable raw materials. In this review, we discuss the structural features that promote antimicrobial activity of amino acid-based surfactants. Monocatenary, dicatenary and gemini surfactants that contain different amino acids on the polar head and show activity against bacteria are revised. The synthesis and basic physico-chemical properties have also been included.
Note: Versió postprint del document publicat a:
It is part of: Advances in Colloid and Interface Science, 2016, vol. 228, p. 17-39
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ISSN: 0001-8686
Appears in Collections:Articles publicats en revistes (Biologia, Sanitat i Medi Ambient)

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