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Title: Maristem stem cells of marine/aquatic invertebrates: from basic research to innovative applications
Author: Ballarin, Loriano
Rinkevich, Baruch
Bartscherer, Kerstin
Burzynski, Artur
Cambier, Sebastien
Cammarata, Matteo
Domart Coulon, Isabelle
Drobne, Damjana
Encinas, Juanma
Frank, Uri
Geneviere, Anne Marie
Hobmayer, Bert
Löhelaid, Helike
Lyons, Daniel
Martínez Serra, Pedro
Oliveri, Paola
Peric, Lorena
Piraino, Stefano
Ramsak, Andreja
Rakers, Sebastian
Rentzsch, Fabian
Rosner, Amalia
da Silva, Tiago Henriques
Somorjai, Ildikó M. L.
Suleiman, Sherif
Coelho, Ana Varela
Keywords: Cèl·lules mare
Invertebrats marins
Stem cells
Marine invertebrates
Issue Date: 15-Feb-2018
Publisher: MDPI
Abstract: The "stem cells" discipline represents one of the most dynamic areas in biomedicine. While adult marine/aquatic invertebrate stem cell (MISC) biology is of prime research and medical interest, studies on stem cells from organisms outside the classical vertebrate (e.g., human, mouse, and zebrafish) and invertebrate (e.g., Drosophila, Caenorhabditis) models have not been pursued vigorously. Marine/aquatic invertebrates constitute the largest biodiversity and the widest phylogenetic radiation on Earth, from morphologically simple organisms (e.g., sponges, cnidarians), to the more complex mollusks, crustaceans, echinoderms, and protochordates. These organisms contain a kaleidoscope of MISC-types that allow the production of a large number of novel bioactive-molecules, many of which are of significant potential interest for human health. MISCs further participate in aging and regeneration phenomena, including whole-body regeneration. For years, the European MISC-community has been highly fragmented and has established scarce ties with biomedical industries in an attempt to harness MISCs for human welfare. Thus, it is important to (i) consolidate the European community of researchers working on MISCs; (ii) promote and coordinate European research on MISC biology; (iii) stimulate young researchers to embark on research in MISC-biology; (iv) develop, validate, and share novel MISC tools and methodologies; (v) establish the MISC discipline as a forefront interest of biomedical disciplines, including nanobiomedicine; and (vi) establish collaborations with industries to exploit MISCs as sources of bioactive molecules. In order to fill the recognized gaps, the EC-COST Action 16203 "MARISTEM" has recently been launched. At its initial stage, the consortium unites 26 scientists from EC countries, Cooperating countries, and Near Neighbor Countries.
Note: Reproducció del document publicat a:
It is part of: Sustainability, 2018, vol. 10, num. 2, p. 526
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ISSN: 2071-1050
Appears in Collections:Articles publicats en revistes (Institut de Recerca de la Biodiversitat (IRBio))
Articles publicats en revistes (Genètica, Microbiologia i Estadística)

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