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dc.contributor.authorVincent, Romaric-
dc.contributor.authorBazellières, Elsa-
dc.contributor.authorPérez González, Carlos-
dc.contributor.authorUroz, Marina-
dc.contributor.authorSerra Picamal, Xavier-
dc.contributor.authorTrepat Guixer, Xavier-
dc.description.abstractA general trait of cell monolayers is their ability to exert contractile stresses on their surroundings. The scaling laws that link such contractile stresses with the size and geometry of constituent cells remain largely unknown. In this Letter, we show that the active tension of an epithelial monolayer scales linearly with the size of the constituent cells, a surprisingly simple relationship. The slope of this relationship defines an active tensile modulus, which depends on the concentration of myosin and spans more than 2 orders of magnitude across cell types and molecular perturbations.-
dc.format.extent5 p.-
dc.publisherAmerican Physical Society-
dc.relation.isformatofReproducció del document publicat a:
dc.relation.ispartofPhysical Review Letters, 2015, vol. 115, num. 24, p. 248103-
dc.rights(c) American Physical Society, 2015-
dc.subject.classificationCèl·lules epitelials-
dc.subject.classificationEstructura molecular-
dc.subject.otherEpithelial cells-
dc.subject.otherMolecular structure-
dc.titleActive Tensile Modulus of an Epithelial Monolayer-
Appears in Collections:Articles publicats en revistes (Biomedicina)
Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC))

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