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http://hdl.handle.net/2445/132887
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DC Field | Value | Language |
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dc.contributor.author | Reynés-Llompart, Gabriel | - |
dc.contributor.author | Gámez, Cristina | - |
dc.contributor.author | Romero-Zayas, Immaculada | - |
dc.contributor.author | Rodríguez-Bel, Laura | - |
dc.contributor.author | Vercher Conejero, José Luís | - |
dc.contributor.author | Martí-Climent, Josep M. | - |
dc.date.accessioned | 2019-05-08T18:07:24Z | - |
dc.date.available | 2019-05-08T18:07:24Z | - |
dc.date.issued | 2017-07 | - |
dc.identifier.issn | 0161-5505 | - |
dc.identifier.uri | http://hdl.handle.net/2445/132887 | - |
dc.description.abstract | The aim of this study was to assess the physical performance of a new PET/CT system, the Discovery IQ with 5-ring detector blocks. Methods: Performance was measured using the National Electrical Manufacturers Association NU2-2012 methodology. Image quality was extended by accounting for different acquisition parameters (lesion-to-background ratios [8:1, 4:1, and 2:1] and acquisition times) and reconstruction algorithms (VUE-point HD [VPHD], VPHD with point-spread-function modeling [VPHD-S], and Q.Clear). Tomographic reconstruction was also assessed using a Jaszczak phantom. Additionally, 30 patient lesions were analyzed to account for differences in lesion volume and SUV quantification between reconstruction algorithms. Results: Spatial resolution ranged from 4.2 mm at 1 cm to 8.5 mm at 20 cm. Sensitivity measured at the center and at 10 cm was 22.8 and 20.4 kps/kBq, respectively. The noise-equivalent counting rate peak was 124 kcps at 9.1 kBq/cm3 The scatter fraction was 36.2%. The accuracy of correction for count losses and randoms was 3.9%. In the image quality test, contrast recovery for VPHD, VPHD-S, and Q.Clear ranged from 18%, 18%, and 13%, respectively (hot contrast; 10-mm sphere diameter; ratio, 2:1), to 68%, 67%, and 81%, respectively (cold contrast; 37-mm sphere diameter; ratio, 8:1). Background variability ranged from 3.4%, 3.0%, and 2.1%, respectively (ratio, 2:1), to 5.5%, 4.8%, and 3.7%, respectively (ratio, 8:1). On Q.Clear reconstruction, the decrease in the penalty term (β) increased the contrast recovery coefficients and background variability. With the Jaszczak phantom, image quality increased overall when a reconstruction algorithm modeling the point-spread function was used, and use of Q.Clear increased the signal-to-noise ratio. Lesions analyzed using VPHD-S and Q.Clear had an SUVmean of 6.5 ± 3 and 7 ± 3, respectively (P < 0.01), and an SUVmax of 11 ± 4.8 and 12 ± 4, respectively (P < 0.01). No significant difference in mean lesion volume was found between algorithms. Conclusion: Among the various Discovery bismuth germanium oxide-based PET/CT scanners, the IQ with 5-ring detector blocks has the highest overall performance, with improved sensitivity and counting rate performance. Q.Clear reconstruction improves the PET image quality, with higher recovery coefficients and lower background variability. | - |
dc.format.extent | 7 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | The Society of Nuclear Medicine and Molecular Imaging | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.2967/jnumed.116.185561 | - |
dc.relation.ispartof | Journal of Nuclear Medicine, 2017, vol. 58, num. 7, p. 1155-1161 | - |
dc.relation.uri | https://doi.org/10.2967/jnumed.116.185561 | - |
dc.rights | (c) The Society of Nuclear Medicine and Molecular Imaging, 2017 | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | Tumors | - |
dc.subject.classification | Diagnòstic per la imatge | - |
dc.subject.classification | Tomografia per emissió de positrons | - |
dc.subject.classification | Imatge corporal | - |
dc.subject.other | Tumors | - |
dc.subject.other | Diagnostic imaging | - |
dc.subject.other | Positron emission tomography | - |
dc.subject.other | Body image | - |
dc.title | Performance characteristics of the whole-body discovery IQ PET/CT system | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 687557 | - |
dc.date.updated | 2019-05-08T18:07:24Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 28302761 | - |
Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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687557.pdf | 940.51 kB | Adobe PDF | View/Open |
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