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http://hdl.handle.net/2445/134285
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DC Field | Value | Language |
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dc.contributor.author | Badia Tahull, Maria Bella | - |
dc.contributor.author | Llop Talaverón, Josep Manuel | - |
dc.contributor.author | Leiva Badosa, Elisabet | - |
dc.contributor.author | Biondo, Sebastián | - |
dc.contributor.author | Farrán Teixidor, Leandre | - |
dc.contributor.author | Ramon Torrell, Josep M. (Josep Maria) | - |
dc.contributor.author | Jódar Masanés, Ramón José | - |
dc.date.accessioned | 2019-05-31T13:25:35Z | - |
dc.date.available | 2019-05-31T13:25:35Z | - |
dc.date.issued | 2010-09 | - |
dc.identifier.issn | 0007-1145 | - |
dc.identifier.uri | http://hdl.handle.net/2445/134285 | - |
dc.description.abstract | n-3 Fatty acids have clinical benefits. The primary aim of the present study was the assessment of infection in patients who underwent major high-risk elective gastrointestinal surgery receiving postoperatively fish oil (FO)-supplemented parenteral nutrition (PN), compared with those receiving a standard olive oil (OO) emulsion. The secondary aims were the assessment of anti-inflammatory response and evaluation of tolerance and safety of these emulsions. A prospective, randomised, double-blind study was performed in patients requiring at least 5 d of PN. An isoenergetic and isoproteic formula was administered: group A received OO alone, while group B received OO that was partially replaced with FO (16.6 %, w/w). End points were outcome measures (mortality, sepsis, infection, hospitalisation days and PN duration), inflammatory response (C-reactive protein (CRP), prealbumin and leucocytes) and safety (TAG and glucose metabolism, and liver and kidney function). Statistical analysis was done using Student's t test and Fisher's exact test (P < 0.05). Twenty-seven patients were evaluated, with thirteen patients receiving FO. In this group, a significantly lower incidence of infections was found (23.1 v. 78.6 %, P = 0.007). CRP, prealbumin and leucocytes were not significantly different between the groups. There were no differences in safety parameters. We conclude that high-risk surgical patients receiving FO-supplemented PN for 5 d present a lower incidence of infection. Emulsions were safe and well tolerated. | - |
dc.format.extent | 5 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Cambridge University Press | - |
dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.1017/S0007114510001066 | - |
dc.relation.ispartof | British Journal of Nutrition, 2010, vol. 104, num. 5, p. 737-741 | - |
dc.relation.uri | https://doi.org/10.1017/S0007114510001066 | - |
dc.rights | (c) Cambridge University Press, 2010 | - |
dc.source | Articles publicats en revistes (Ciències Clíniques) | - |
dc.subject.classification | Agents antiinfecciosos | - |
dc.subject.classification | Cirurgia | - |
dc.subject.classification | Malalties del tracte gastrointestinal | - |
dc.subject.classification | Alimentació parenteral | - |
dc.subject.classification | Ús terapèutic | - |
dc.subject.classification | Emulsions | - |
dc.subject.classification | Olis de peix | - |
dc.subject.classification | Cura postoperatòria | - |
dc.subject.classification | Programes de prevenció | - |
dc.subject.other | Anti-infective agents | - |
dc.subject.other | Surgery | - |
dc.subject.other | Gastrointestinal system diseases | - |
dc.subject.other | Parenteral feeding | - |
dc.subject.other | Therapeutic use | - |
dc.subject.other | Emulsions | - |
dc.subject.other | Fish oils | - |
dc.subject.other | Postoperative care | - |
dc.subject.other | Prevention programs | - |
dc.title | A randomised study on the clinical progress of high-risk elective major gastrointestinal surgery patients treated with olive oil-based parenteral nutrition with or without a fish oil supplement | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 589931 | - |
dc.date.updated | 2019-05-31T13:25:35Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 20350344 | - |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) Articles publicats en revistes (Ciències Clíniques) Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) |
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File | Description | Size | Format | |
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589931.pdf | 80.7 kB | Adobe PDF | View/Open |
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