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Title: Microbiological profile of ozenoxacin
Author: Morrissey, Ian
Cantón, Rafael
Vila Estapé, Jordi
Gargallo Viola, Domingo
Zsolt, Ilonka
García Castillo, María
López, Yuly
Keywords: Infeccions respiratòries
Respiratory infections
Issue Date: 28-May-2019
Publisher: Future Science Group
Abstract: Aim: To explore the antibacterial spectrum of ozenoxacin and compare its in vitro activity with that of other antibacterial agents. Materials & methods: In 2010, 10,054 isolates were collected from 128 centers worldwide. Minimum inhibitory concentrations against Gram-positive and Gram-negative isolates were determined for 23 and 13 antibacterial agents, respectively. Results: Ozenoxacin exhibited high in vitro activity against susceptible, and methicillin- or levofloxacin-resistant, Gram-positive bacteria. Ozenoxacin was one or two dilutions less active against Enterobacteriaceae isolates, except for Escherichia coli, than other quinolones. Conclusion: Ozenoxacin is a potent antimicrobial agent mainly against susceptible and resistant strains of Gram-positive isolates (staphylococci and streptococci), and shows activity against some Gram-negative isolates.
Note: Reproducció del document publicat a:
It is part of: Future Microbiology, 2019
Related resource: 10.2217/fmb-2019-0089
ISSN: 1746-0913
Appears in Collections:Articles publicats en revistes (ISGlobal)

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