Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/137177
Title: Intracellular electrochemical sensing
Author: Ino, Kosuke
Nashimoto, Yuji
Taira, Noriko
Ramon Azcon, Javier
Shiku, Hitoshi
Keywords: Anàlisi electroquímica
Nanoelectrònica
Electrochemical analysis
Nanoelectronics
Issue Date: 25-Jul-2018
Publisher: Wiley
Abstract: Observing biochemical processes within living cell is imperative for biological and medical research. Fluoresce imaging is widely used for intracellular sensing of cell membranes, nuclei, lysosomes, and pH. Electrochemical assays have been proposed as an alternative to fluorescence-based assays because of excellent analytical features of electrochemical devices. Notably, thanks to the rapid progress of micro/nanotechnologies and electrochemical techniques, intracellular electrochemical sensing is making rapid progress, leading to a successful detection of intracellular components. Such insight can provide a deep understanding of cellular biological processes and, ultimately, define the human healthy and diseased states. In this review, we present an overview of recent research progress in intracellular electrochemical sensing. We focus on two main topics, electrochemical extraction of cytosolic contents from cells and intracellular electrochemical sensing in situ.
Observing biochemical processes within living cell is imperative for biological and medical research. Fluoresce imaging is widely used for intracellular sensing of cell membranes, nuclei, lysosomes, and pH. Electrochemical assays have been proposed as an alternative to fluorescence‐based assays because of excellent analytical features of electrochemical devices. Notably, thanks to the rapid progress of micro/nanotechnologies and electrochemical techniques, intracellular electrochemical sensing is making rapid progress, leading to a successful detection of intracellular components. Such insight can provide a deep understanding of cellular biological processes and, ultimately, define the human healthy and diseased states. In this review, we present an overview of recent research progress in intracellular electrochemical sensing. We focus on two main topics, electrochemical extraction of cytosolic contents from cells and intracellular electrochemical sensing in situ.
Note: Versió postprint del document publicat a: https://doi.org/10.1002/elan.201800410
It is part of: Electroanalysis, 2018, vol. 30, num. 10, p. 2195-2209
URI: http://hdl.handle.net/2445/137177
Related resource: https://doi.org/10.1002/elan.201800410
Appears in Collections:Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC))

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