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Title: Anti-Inflammatory Nutrition and Successful Ageing in Elderly Individuals: The Multinational MEDIS Study
Author: Tyrovolas, Stefanos
Haro Abad, Josep Maria
Foscolou, Alexandra
Tyrovola, Dimitra
Mariolis, Anargiros
Bountziouka, Vassiliki
Piscopo, Suzanne
Valacchi, Giuseppe
Anastasiou, Foteini
Gotsis, Efthimios
Metallinos, George
Papairakleous, Natassa
Polychronopoulos, Evangelos
Matalas, Antonia Leda
Lionis, Christos
Zeimbekis, Akis
Tur, Josep Antoni
Sidossis, Labros S.
Panagiotakos, Demosthenes B.
MEDIS Study Group
Keywords: Envelliment
Persones grans
Mediterrània (Regió)
Older people
Mediterranean Region
Issue Date: 2018
Publisher: Karger
Abstract: Abstract BACKGROUND: The role of diet and inflammation in successful ageing is not transparent, and as such, is still being investigated. The aim of the present work was to evaluate the inflammatory potential of dietary habits in the successful ageing of a random sample of older adults living in the Mediterranean basin and who participated in the MEDIS (MEDiterranean ISlands) study. METHODS: During 2005-2016, 3,128 older adults (aged 65-100 years) from 24 Mediterranean islands and the rural Mani region (Peloponnesus) of Greece were enrolled in the study. A multidimensional successful ageing index consisting of 10 components was employed. A validated and reproducible Food Frequency Questionnaire (FFQ) was used to evaluate the dietary habits of the older adults. A nutrition anti-inflammatory (NAI) score based on the participants' specific dietary habits was assessed. RESULTS: Participants with high NAI scores (proinflammatory nutrition) had a higher prevalence of hypercholesterolemia and lower levels of successful ageing. After adjusting for several confounders, the NAI score was associated with successful ageing (-0.03, 95% CI -0.5 to -0.006). Stratified analysis by gender and advanced age revealed heterogeneity in the NAI score, predicting successful ageing. CONCLUSIONS: The inflammatory potential of nutrition was reported as an important factor for successful ageing, suggesting that further research is needed on the role of anti- and proinflammatory dietary habits in healthy and successful ageing.
Note: Versió postprint del document publicat a:
It is part of: Gerontology, 2018, vol. 64, num. 1, p. 3-10
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ISSN: 0304-324X
Appears in Collections:Articles publicats en revistes (Medicina)

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