Please use this identifier to cite or link to this item: http://hdl.handle.net/2445/138499
Title: Novel cyclometallated iridium catalysts for asymmetric hydrogenation of N-methyl and N-phenyl imines
Other Titles: Nous catalitzadors ciclometal·lats d’iridi per hidrogenacions asimètriques d’N-metil i N-fenil imines
Author: Fernández Sabaté, Marc
Director/Tutor: Verdaguer i Espaulella, Xavier
Salomó i Prat, Ernest
Rojo Solé, Josep Ma.
Keywords: Iridi
Hidrogenació
Treballs de fi de grau
Iridium
Hydrogenation
Bachelor's thesis
Issue Date: Jun-2019
Abstract: In this work, three acetophenone N-phenyl imine derivatives functionalized in the para position have been prepared and cyclometallated to Ir-MaxPHOX catalyst. One of the additives has a hydrogen bond acceptor group, while the others have bulky substituents. The behavior of these compounds in asymmetric hydrogenation of acetophenone N-methyl and N-phenyl imine substrates has been studied. The additive containing a hydrogen bond acceptor provided better enantioselectivity than the others. This reinforces the hypothesis that a hydrogen bond interaction between the catalyst and the substrate would increase the selectivity. Additives with bulky substituents provided worse results, probably due to steric hindrance, decreasing the selectivity
Note: Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2019, Tutors: Xavier Verdaguer Espaulella, Ernest Salomó i Prat, Josep Mª Rojo Solé
URI: http://hdl.handle.net/2445/138499
Appears in Collections:Treballs Finals de Grau (TFG) - Química

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